Lifetime overweight and adult asthma

1978/1979 Ribeirão Preto Birth Cohort, São Paulo, Brazil

Bibliographic Data

ID5168622
AuthorsLuana Lopes Padilha (0000-0002-7162-2726, Universidade Federal do Maranhão), Cecilia Cláudia Costa Ribeiro (0000-0003-0041-7618, Universidade Federal do Maranhão), Joelma Ximenes Prado Teixeira Nascimento (0000-0002-2871-8685, Universidade Federal do Maranhão), Vanda Maria Ferreira Simões (0000-0001-8351-1348, Universidade Federal do Maranhão), Fernanda Pino Vitti (0000-0002-3309-183X, Universidade de São Paulo), Viviane Cunha Cardoso (0000-0002-2677-5600, Universidade de São Paulo), Elcio Oliveira Vianna (0000-0003-1902-6326, Universidade de São Paulo), Marco A Barbieri (0000-0001-8060-1428, Universidade de São Paulo), Antonio Augusto Moura Da Silva (0000-0003-4968-5138, Universidade Federal do Maranhão), Heloísa Bettiol (0000-0001-8744-4373, Universidade de São Paulo)
Year2020
Volume36
Issue3
Pagese00041519-e00041519
Publication date2020-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueCadernos de Saude Publica (JOURNAL)
Journal identifiersISSN: 0102-311X • E-ISSN: 1678-4464
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/0102-311x00041519
PMID32187287
OpenAlexW3010663834
SCIELO_PIDS0102-311X2020000305002
LanguageEN
Citations received1
References cited51

Studies focusing on obesity and asthma frequently consider the weight at a given time; thus, modeling pathways through lifetime overweight may contribute to elucidate temporal aspects in this relationship. This study modeled the pathways in the association of lifetime overweight with asthma in adult life, using data from the 1978/1979 Birth Cohort, Ribeirão Preto, São Paulo, Brazil (n = 2,063) at birth (baseline), school age (9/11 years) and adult age (23/25 years). A theoretical model was proposed to explore the effects of lifetime overweight on asthma in adult life analyzed by structural equation modeling. Parental obesity (SC - standardized coefficenttotal = 0.211, p < 0.001; SCdirect = 0.115, p = 0.007) and overweight at school age (SCtotal = 0.565, p < 0.0001; SCdirect = 0.565, p < 0.0001) were associated with overweight in adult life. Parental obesity (SCdirect = 0.105, p = 0.047) and nutritional status at birth (SCtotal = -0.124, p = 0.009; SCdirect = -0.131, p = 0.007) were associated with asthma in adult life. A higher "current adult socieconomic situation" was inversely associated to overweight (SCdirect = -0.171, p = 0.020) and to asthma in adult life (SCtotal = -0.179, p = 0.041; SCdirect = -0.182, p = 0.039). Parental obesity showed a transgenerational effect in weight, triggering to childhood and adulthood overweight. Parallel to underweight at birth, parental obesity was also a risk to asthma in adult life. While, the socioeconomic status in adult life protected from both, overweight and asthma

Asthma · Cohort · Cohort study · Environmental health · Obesity · Overweight · Sociology · Breastfeeding Practices and Influences · Demography · Internal Medicine · Medicine · Noise Effects and Management · Obesity, Physical Activity, Diet · Gerontology