Rapid tests for diagnosing syphilis
Validation in an STD clinic in the Amazon Region, Brazil
Bibliographic Data
| ID | 5175607 |
|---|---|
| Authors | Adele Schwartz Benzaken (0000-0002-5789-0695, Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Brasil), Enrique Galbán García (Universidad Calixto Garcia, Cuba), José Carlos Gomes Sardinha (Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Brasil), José Carlos Sardinha (0000-0003-2177-0904), João Catarino Dutra Junior (Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta, Brasil), João Catarino Dutra, Rosanna Peeling (World Health Organization), Rosanna Ŵ Peeling (0000-0001-7404-8873, World Health Organization - Pakistan) |
| Year | 2007 |
| Volume | 23 |
| Issue | suppl 3 |
| Pages | S456-S457 |
| Publication date | 2007-01-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s0102-311x2007001500013 |
| PMID | 17992351 |
| OpenAlex | W2100171667 |
| SciELO | S0102-311X2007001500013 |
| Language | EN |
| Citations received | 1 |
| References cited | 9 |
Correct, early diagnosis and treatment of syphilis are essential for its control. Traditional diagnostic tests depend on specialized equipment, installations, and human resources. In the search for quick, simple tests, a project was conducted on the validation and reproducibility of four different tests, previously assessed by WHO reference laboratories. The study also verified the operational characteristics and acceptance by patients and health professionals. Samples obtained at an STD clinic were from 541 and 248 patients with 51 and 52 positive results according to FTA-Abs (gold standard) in studies 1 and 2, respectively. The sensitivity varied from 84 to 96%, specificity was greater than 98%, and PPV was > 90%. Reproducibility was > 97% and kappa index 0.94, comparing the results obtained by different health workers. The tests took less than 20 minutes to perform, and more than 90% of patients agreed to wait up to two hours for the results. The tests presented the necessary requirements for use in diagnosis of syphilis, thus providing an additional option for controlling this disease
Amazon rainforest · Diagnostic test · Disease control · Environmental health · Family medicine · Gold standard (test) · Human immunodeficiency virus (HIV) · Kappa · Medical physics · Reproducibility · Statistics · Syphilis · HIV/AIDS Research and Interventions · Internal Medicine · Medicine · Reproductive tract infections research · Syphilis Diagnosis and Treatment · Pediatrics
| Citations per year | 0.06 |
|---|---|
| Citation span | 2009 - 2009 (1) |
| Highly cited | No |