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Rifampicin Induced Chromatid Exchanges in Mouse Bone Marrow Cells

Bibliographic Data

ID5220276
AuthorsAmarjot K Chhabra (Guru Nanak Dev University), A J S Bhanwar (Guru Nanak Dev University)
Year1996
Volume7
Issue3
Pages219-220
Publication date1996-07-01
Open AccessYes
TypeARTICLE
VenueJournal of Human Ecology (JOURNAL)
Journal identifiersISSN: 0970-9274 • E-ISSN: 2456-6608
PublisherKamla Raj Enterprises (PUBLISHER)
DOI10.1080/09709274.1996.11907224
OpenAlexW2768452755
LanguageEN
References cited2

Mice were injected i.p. with Single dose of 0.5. 2.5. 5 mg/kg body of weight of rifampicin. Cells were sampled for mitotic chromosome analysis 4, 16 and 24 h after treatment. The maximal yield of chromosome type aberrations induced was found 24 h after treatment. More than 60% of the cells carried at least one chromatid exchange. The majority of these were exchanges derived from breaks in the centromeric heterochromatin

Antibiotics · Biology · Bone marrow · Chromatid · Chromosome · Heterochromatin · Mitosis · Rifampicin · Chemistry · Chromosomal and Genetic Variations · DNA and Nucleic Acid Chemistry · Genomic variations and chromosomal abnormalities · Cell Biology · Genetics · Immunology · Molecular Biology

Highly citedNo

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