Factors associated with asymptomatic infection in family members and neighbors of patients with visceral leishmaniasis
Bibliographic Data
| ID | 5223899 |
|---|---|
| Authors | Germano Silva Moura (0000-0003-0404-2331, Universidade Federal do Maranhão), Alcione Miranda Dos Santos (0000-0001-9711-0182, Universidade Federal do Maranhão), Dorlene Maria Cardoso De Aquino (0000-0002-9604-052X, Universidade Federal do Maranhão), Antonio Augusto Moura Da Silva (0000-0003-4968-5138, Universidade Federal do Maranhão), Arlene De Jesus Mendes Caldas (0000-0001-7087-8781, Universidade Federal do Maranhão) |
| Year | 2012 |
| Volume | 28 |
| Issue | 12 |
| Pages | 2306-2314 |
| Publication date | 2012-12-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/s0102-311x2012001400009 |
| PMID | 23288063 |
| OpenAlex | W2056060242 |
| SciELO | S0102-311X2012001400009 |
| Language | EN |
| References cited | 20 |
This study analyzed factors associated with asymptomatic Leishmania chagasi infection in family members and neighbors of patients with visceral leishmaniasis (VL). A cross-sectional study was conducted with 361 individuals in the counties comprising Ilha de São Luís (São Luís Island) in Maranhão State, Brazil. The Montenegro skin test (MST) and serology by enzyme-linked immunosorbent assay (ELISA) were performed to detect infection. Odds ratios (OR) and prevalence ratios (PR) and their 95% confidence intervals (95%CI) were estimated by multilevel logistic regression and Poisson regression, respectively. The rates of positive reactions were 71.3% for MST and 9.7% for ELISA. The variable associated with infection according to MST was living in the same household as the index case (PR = 1.36; 95%CI: 1.03-1.78). According to ELISA, the statistically significant variables were: living in the county of Raposa (OR = 3.56; 95%CI: 1.24-10.19) and living in the same household as the index case (OR = 2.70; 95%CI: 1.19-6.08). Family members of individuals with LV are at increased risk of infection. Priority control measures should target these families
Antibody · Asymptomatic · Confidence interval · Cross-sectional study · Environmental health · Leishmania chagasi · Leishmaniasis · Logistic regression · Odds ratio · Pathology · Poisson regression · Population · Serology · Visceral leishmaniasis · Demography · Epidemiology · Immunology · Internal Medicine · Medicine · Parasites and Host Interactions · Research on Leishmaniasis Studies · Trypanosoma species research and implications
Alternatives for logistic regression in cross-sectional studies
Tegumentary and visceral leishmaniases in Brazil
Prevalência de infecção por Leishmania chagasi utilizando os métodos de Elisa (rK39 e CRUDE) e intradermorreação de Montenegro em área endêmica do Maranhão, Brasil
Asymptomatic infection in family contacts of patients with human visceral leishmaniasis in Três Lagoas, Mato Grosso do Sul State, Brazil
| Highly cited | No |
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