Clinical and evolving features of women diagnosed with precancerous cervical lesions, screened and treated in the Amazon region of Brazil
Bibliographic Data
| ID | 5232720 |
|---|---|
| Authors | Patrícia Rezende Do Prado (0000-0002-3563-6602, Universidade Federal do Acre), Rosalina Jorge Koifman (0000-0002-2746-7597, Fundação Oswaldo Cruz), Rosalina Koifman (0000-0003-4391-4542, Fundação Oswaldo Cruz), Ilce Ferreira Da Silva (0000-0002-7134-3030, Fundação Oswaldo Cruz) |
| Year | 2014 |
| Volume | 30 |
| Issue | 9 |
| Pages | 1912-1920 |
| Publication date | 2014-09-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Cadernos de Saude Publica (JOURNAL) |
| Journal identifiers | ISSN: 0102-311X • E-ISSN: 1678-4464 |
| Publisher | FapUNIFESP (SciELO) (PUBLISHER) |
| DOI | 10.1590/0102-311x00164913 |
| PMID | 25317520 |
| OpenAlex | W2012178718 |
| SciELO | S0102-311X2014000901912 |
| Language | EN |
| References cited | 11 |
The objective of the study was to determine the dynamics of precancerous lesions in women of a cohort treated for cervical intraepithelial neoplasia (CIN) and followed up over the next two years. The conditional probability of failure was calculated using the Kaplan-Meier method, and the raw and adjusted hazard ratios (HR) were determined using Cox regression with a p-value entry of < 0.05. Of the 237 women who were treated, 51.5% were accompanied over 24 months, and treatment failed for 21.9% of those accompanied. Women who had five or more pregnancies (adjusted HR = 3.10, 95%CI: 1.28-7.51) or an initial histological diagnosis of CIN II/III demonstrated an independent risk of treatment failure (adjusted HR = 3.14, 95%CI: 1.20-8.19). Being in a stable relationship was a protective factor against treatment failure (adjusted HR = 0.47, 95%CI: 0.24-0.89). A history of more frequent pregnancies and a histological diagnosis of CIN II/III are directly correlated with risk of CIN treatment failure, whereas being in a stable relationship is inversely correlated with this risk
Amazon rainforest · Biology · Cancer · Cervical cancer · Colposcopy · Gynecology · Cervical Cancer and HPV Research · Dermatology · Global Cancer Incidence and Screening · Internal Medicine · Medicine · Women's cancer prevention and management
Estimates of worldwide burden of cancer in 2008
Global cancer statistics
Fatores associados ao câncer do colo uterino em Propriá, Sergipe, Brasil
Caracterização da demanda de pacientes com carcinoma de colo uterino no Hospital das Clínicas da Universidade Federal de Uberlândia, Minas Gerais, Brasil, 1984-1988
Prevalência do exame preventivo de câncer do colo do útero em Rio Branco, Acre, Brasil, e fatores associados à não-realização do exame
| Highly cited | No |
|---|