Association between cytosolic low molecular weight phosphotyrosine-phosphatase and malaria?a possible mechanism
Bibliographic Data
| ID | 5233022 |
|---|---|
| Authors | E Bottini (0000-0003-1723-9723, University of Rome Tor Vergata, corresponding author) |
| Year | 1999 |
| Volume | 108 |
| Issue | 2 |
| Pages | 241-244 |
| Publication date | 1999-02-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/(sici)1096-8644(199902)108:2<241::aid-ajpa9>3.0.co;2-z |
| PMID | 9988385 |
| OpenAlex | W2062842721 |
| Language | EN |
| Citations received | 2 |
| References cited | 11 |
Cytosolic low molecular weight phosphotyrosine-phosphatase shows dephosphorylating activity of the band 3 protein. Increased phosphorylation of this protein increases membrane rigidity and resistance to invasion of red blood cells by malarial parasites. This observation may explain the negative association previously reported by our group between the high activity *C allele of cytosolic low molecular weight phosphotyrosine-phosphatase and past malarial morbidity.
Association (psychology) · Biology · Cytosol · Enzyme · Malaria · Mechanism (biology) · Phosphatase · Phosphorylation · Biochemistry · Cell Biology · Chemistry · Immunology · Malaria Research and Control · Parasites and Host Interactions · Psychology · Research on Leishmaniasis Studies
| Citations per year | 0.08 |
|---|---|
| Citation span | 2000 - 2001 (2) |
| Highly cited | No |