HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil

Bibliographic Data

ID5270767
AuthorsInes Dourado (0000-0003-1675-2146, Universidade Federal da Bahia), Craig A Milroy (Universidade Federal da Bahia), Craig Milroy (Universidade Federal da Bahia), Marco Antônio Gomes Mello (Fundação Oswaldo Cruz, Brasil; Fundação Bahiana para o Desenvolvimento das Ciências, Brasil), Geraldo Argolo Ferraro (Fundação Oswaldo Cruz, Brasil; Fundação Bahiana para o Desenvolvimento das Ciências, Brasil), Humberto Castro-Lima Filho (Fundação Oswaldo Cruz, Brasil; Fundação Bahiana para o Desenvolvimento das Ciências, Brasil), Humberto Castro‐Lima (0000-0002-2688-6319, Escola Bahiana de Medicina e Saúde Pública), Monick Lindenmeyer Guimarães (0000-0002-8442-3427, Fundação Oswaldo Cruz), Mariza Gonçalves Morgado (0000-0002-9304-6184, Fundação Oswaldo Cruz), Marli Geralda Teixeira (0000-0003-3318-3408, Universidade Federal da Bahia), Maria Glória Teixeira, Maurício Lima Barreto (0000-0002-0215-4930, Universidade Federal da Bahia), Bernardo Galvão-Castro (0000-0002-0644-6471, Fundação Oswaldo Cruz, Brasil; Fundação Bahiana para o Desenvolvimento das Ciências, Brasil)
Year2007
Volume23
Issue1
Pages25-32
Publication date2007-01-01
Open AccessYes
TypeARTICLE
VenueCadernos de Saude Publica (JOURNAL)
Journal identifiersISSN: 0102-311X • E-ISSN: 1678-4464
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/s0102-311x2007000100004
PMID17187101
OpenAlexW2147754637
SciELOS0102-311X2007000100004
LanguageEN
Citations received5
References cited22

To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750

Environmental health · Geography · Human immunodeficiency virus (HIV) · Population · Seroprevalence · Socioeconomics · Sociology · Demography · HIV Research and Treatment · HIV/AIDS oral health manifestations · HIV/AIDS Research and Interventions · Medicine · Virology

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