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Multiple myeloma in Brazil

An assessment of Global Burden Disease study 2019

Bibliographic Data

ID5333998
AuthorsMax Moura De Oliveira (0000-0002-0804-5145, Universidade Federal de Goiás), Guilherme Augusto Veloso (0000-0002-5348-3793, Universidade Federal Fluminense), Deborah Carvalho Malta (0000-0002-8214-5734, Universidade Federal de Minas Gerais), Maria Paula Curado (0000-0001-8172-2483, A.C.Camargo Cancer Center Epidemiologia, Brasil), Cristiane A Menezes De Pádua (0000-0001-7083-3188, Universidade Federal de Minas Gerais)
Year2024
Volume48
Issue142
Publication date2024-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueSaúde em Debate (JOURNAL)
Journal identifiersISSN: 0103-1104 • E-ISSN: 2358-2898
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/2358-289820241428855i
OpenAlexW4403606800
SCIELO_PIDS0103-11042024000300212
LanguageEN
References cited20

Multiple myeloma is the second most common hematological cancer; it accounts for approximately 10% of all hematologic malignancies and 1%-2% of all cancer diagnoses. From 1990 to 2019, an ecological study was conducted to describe and evaluate trends in Brazil's morbidity, mortality, and disease. The Global Burden of Disease data described age-standardized (+40 years) incidence, prevalence, mortality, disability-adjusted life years, and its components in Brazil and across its 27 federative units according to sex and Socio-demographic Index quintiles. Trends were estimated using linear regression and expressed as Average Annual Percentage Changes (AAPC) and 95% Confidence Intervals (CI). Ascending trends of the measures were found for both sexes in Brazil and its federative units. Mortality increased to a lesser extent than incidence (AAPC=1.3%; 95%CI=1.2-1.3 vs. AAPC=1.5%; 95%CI= 1.5-1.5 for men; AAPC=0.9%; 95%CI=0.9-0.9 vs. AAPC=1.1%; 95%CI=1.1-1.2 for women), resulting in higher rising trends in prevalence for both sexes. All the measures were significantly higher in high- and high-middle socio-demographic quintiles; however, higher ascending trends were found in lower socio-demographic quintiles. Aging, level of development, diagnosis, and treatment appear to explain Brazil's ascending multiple myeloma rates and their differences among the federative units

Burden of disease · Disease · Disease burden · Multiple myeloma · Internal Medicine · Medicine · Multiple Myeloma Research and Treatments · Public Health in Brazil

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