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Do Financial Conflicts of Interest Bias Research

An Inquiry into the “Funding Effect” Hypothesis

Bibliographic Data

ID5338303
AuthorsSheldon Krimsky (0000-0002-0647-9951, Tufts University, corresponding author)
Year2013
Volume38
Issue4
Pages566-587
Publication date2013-07-01
Open AccessYes
TypeARTICLE
VenueScience Technology & Human Values (JOURNAL)
Journal identifiersISSN: 0162-2439 • E-ISSN: 1552-8251
PublisherSAGE Publications Inc (PUBLISHER)
DOI10.1177/0162243912456271
OpenAlexW2153909042
LanguageEN
Citations received22
References cited24

In the mid-1980s, social scientists compared outcome measures of related drug studies, some funded by private companies and others by nonprofit organizations or government agencies. The concept of a "funding effect" was coined when it was discovered that study outcomes could be statistically correlated with funding sources, largely in drug safety and efficacy studies. Also identified in tobacco research and chemical toxicity studies, the "funding effect" is often attributed, implicitly or explicitly, to research bias. This article discusses the meaning of scientific bias in research, examines the strongest evidence for the "funding effect," and explores the question of whether the "funding effect" is an indicator of biased research that is driven by the financial interests of the for-profit sponsor. This article argues that the "funding effect" is merely a symptom of the factors that could be responsible for outcome disparities in product assessment. Social scientists should not suspend their skepticism and choose as a default hypothesis that bias is always or typically the cause

Business · Economics · Political science · Positive economics · Public economics · Public relations · Skepticism · Meta-analysis and systematic reviews · Pharmaceutical industry and healthcare · scientometrics and bibliometrics research

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Citation span2014 - 2026 (13)
Highly citedNo

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