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Stalled Scale-Up of Opioid Agonist Therapies for HIV Prevention in Kazakhstan

History, Policy, and Recommendations for Change

Bibliographic Data

ID5710847
AuthorsAnatoly Liberman (0000-0002-3998-4313, Yale University, corresponding author), Roman Ivasiy (0000-0002-8405-1360), Frederick L Altice (0000-0002-7860-693X), Daniel Bromberg (0000-0003-0584-7238, Yale University, corresponding author), Oxana Ibragimova (0000-0002-9459-2478, corresponding author), Zhaniya Seksenova (Ministry of Health of the Republic of Kazakhstan, corresponding author), Lynn Madden (0000-0002-9981-3938, Yale University, corresponding author), Sholpan Primbetova (0000-0002-7633-7764), Assel Terlikbayeva (0000-0002-4067-1998, corresponding author)
Year2024
Volume5
Issue2
Pages69-77
Publication date2024-01-10
Open AccessYes
TypeARTICLE
VenueJournal of Illicit Economies and Development (JOURNAL)
Journal identifiersISSN: 2516-7227 • E-ISSN: 2516-7227
PublisherLSE Press (PUBLISHER • GB)
DOI10.31389/jied.208
OpenAlexW4390702703
LanguageEN
Citations received2
References cited12

HIV incidence and mortality are increasing in Eastern Europe and Central Asia and are concentrated in people who inject drugs. Maintenance with opioid agonist therapies (OAT) like methadone or buprenorphine is the best treatment for opioid use disorder and a key HIV-prevention strategy in the region. In Kazakhstan, the scale-up of methadone has been minimal since methadone’s introduction in 2008 and has been supported through international charitable organizations. As the Republic of Kazakhstan is designated to assume financial and administrative oversight of OAT, legislative gains can ensure treatment continuity and scale-up. Here, we review legislative barriers to OAT scale-up in Kazakhstan using an implementation science lens. We review legislative, political, and cultural barriers that undermine the efficient distribution and allocation of medications and impose burdensome clinical and administrative demands on patients and clinicians. Legislative reform is required to support further OAT expansion. We therefore provide policy recommendations to overcome these barriers to increase access to this life-saving, life-prolonging, evidence-based medical treatment. Minimally, these include increased numbers of clinical sites and patients at these sites; re-engineering OAT delivery across the country and directly to patients; introducing newer formulations of OAT; and creating an open bidding process to procure treatment medications

Agonist · Family medicine · Geography · Opioid · Receptor · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Opioid Use Disorder Treatment · Internal Medicine

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Citations per year1
Citation span2024 - 2026 (3)
Highly citedNo

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Open DOIOpen Access
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