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Sex moderates associations between prenatal glucocorticoid exposure and human fetal neurological development

Bibliographic Data

ID5772504
AuthorsLaura M Glynn (0000-0001-5903-8685, University of California, Irvine), Curt A Sandman (0000-0003-3876-8528, Chapman University)
Year2012
Volume15
Issue5
Pages601-610
Publication date2012-06-27
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueDevelopmental Science (JOURNAL)
Journal identifiersISSN: 1363-755X • E-ISSN: 1467-7687
PublisherWiley (PUBLISHER • GB)
DOI10.1111/j.1467-7687.2012.01159.x
PMID22925508
OpenAlexW1495711594
LanguageEN
Citations received7
References cited55

Maternal cortisol levels (at 15, 19, 25, 31 and 37 weeks' gestation) and fetal movement response to vibroacoustic stimulation (VAS; at 25, 31 and 37 weeks) were assessed in 190 mother-fetus pairs. Fetuses showed a response to the VAS at 25 weeks and there was evidence of increasing maturation in the response at 31 and 37 weeks. Early elevations in cortisol predicted a failure to respond to the VAS at 25 weeks and later elevations in cortisol were associated with a larger response among fetuses when assessed near term. The associations between cortisol and VAS emerged earlier and were more apparent among female fetuses than among the males. The findings provide support for the role of prenatal glucocorticoids in shaping human fetal CNS development

Prenatal development · Birth, Development, and Health · Infant Development and Preterm Care · Neonatal Respiratory Health Research

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Unique citing works7
Citations per year0,54
Citation span2013 - 2024 (12)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 7

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