Assessment of the Relationship Between Subcutaneous Fat Tissue and Results of Electromyoneurography

In this cross-sectional study we assessed the associations between the amplitude and the velocity of the potential and the volume of subcutaneous fat tissue in order to answer the question on whether the results of electroneuromyography should be adjusted for the volume of subcutaneous fat tissue in analytical studies. The sample consisted of 570 individuals who were covered by the seriveces of the policlinic of the International Kazakh-Turkish University, Turkestan, Kazakhstan. Peripheral neuropathy was assessed using a modified Neuropathy Disability Score (NDSm). The volume of the subcutaneous fat tissue was calculated using the formula proposed by Bonora (1995). Associations between the volume of subcutaneous fat tissue and the indices of the electroneuromyography were assessed using multivariable linear regression analyses. Amplitude and velocity of the potential were separately used as dependent variables. Crude and adjusted regression coefficients were calculated with 95 % confidence intervals (CI). Analyses were performed separately for participants with and without other symptoms of peripheral neuropathy. The prevalence of peripheral neuropathy in the sample was 11.4 (95 % CI: 9.1; 14.3) %. We observed inverse and statistically significant associations between the volume of subcutaneous fat tissue and the amplitude of the potential in n. peroneus, n. tibialis and n. suralis among the individuals with and without other signs of peripheral neuropathy. However, we did not observe independent associations between the velocity of the electric wave and the volume of subcutaneous fat tissue. The results of our study demonstrate the need in additional adjustment for the volume of subcutaneous fat tissue in studies in studies with the use of electroneuromyography for example is studies on neuropathy among patients with Type II diabetes mellitus or metabolic syndrome to control for the confounding effect of the former

Adipose tissue · Confidence interval · Diabetes mellitus · Electromyoneurography · Peripheral · Peripheral neuropathy · Subcutaneous fat · Subcutaneous tissue · Body Contouring and Surgery · Diabetic Foot Ulcer Assessment and Management · Medicine · Skin Diseases and Diabetes · Endocrinology · Internal Medicine · Surgery