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Weinberg's Differential Rule Reconsidered

Bibliographic Data

ID6068045
AuthorsJohan Fellman (0000-0002-7162-7121, Institute of Genetics), Aldur W Eriksson
Year2006
Volume78
Issue3
Pages253-275
Publication date2006-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueHuman Biology (JOURNAL)
Journal identifiersISSN: 0018-7143 • E-ISSN: 1534-6617
PublisherProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2006.0044
PMID17216800
OpenAlexW2169301639
LanguageEN
Citations received8
References cited4

A central problem in research on twins is the estimation of the rates of monozygotic and dizygotic twin maternities. The estimation usually follows Weinberg's differential rule. According to this rule, the rate of dizygotic twinning is twice the rate of twin maternities in which the twins are of opposite sex. The monozygotic twinning rate is the difference between the rates of same-sex and opposite-sex twin sets. Weinberg's differential rule is implicitly based on the assumptions that the probability of a male equals the probability of a female and that the sexes in a dizygotic twin set are independent. Although Weinberg's differential rule has been the target of continuing discussions, the reliability of these assumptions has never been conclusively verified or rejected. In this study we present new variance formulas for the monozygotic and dizygotic twinning rates obtained using Weinberg's differential rule and stress that these new formulas have to be used. We analyze the accuracy of Weinberg's differential rule by considering alternative attempts. Especially, we build a general likelihood function and show that the maximum-likelihood estimates differ only slightly from the rates obtained using Weinberg's differential rule. In addition, our methods are applied to twinning data from Finland and Sweden. We compare our results with findings in the literature. In conclusion, our findings indicate that Weinberg's differential rule is rather robust and that despite its simplicity, it gives reliable results when official birth registers are analyzed

Biology · Crystal twinning · Differential (mechanical device) · Dizygotic twins · Econometrics · Function (biology) · Obstetrics · Physics · Pregnancy · Singleton · Statistics · Assisted Reproductive Technology and Twin Pregnancy · Demographic Trends and Gender Preferences · Family Dynamics and Relationships · Genetics · Mathematics · Medicine

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Unique citing works8
Citations per year0,44
Citation span2008 - 2026 (19)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 6

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