Patterns of Genetic Diversity at the Nine Forensically Approved STR Loci in the Indian Populations
Bibliographic Data
| ID | 6068293 |
|---|---|
| Authors | Ranjan Dutta (0000-0001-8502-4455), Dutta Ranjan (Center for Human Genetics), B Mohan Reddy, P Chattopadhyay, Pratima Chaudhuri (0000-0002-5723-4428), K Kashyap, V K Kashyap (0009-0004-2396-1485), Guangyun Sun, Ranjan Deka (0000-0003-2680-1159) |
| Year | 2002 |
| Volume | 74 |
| Issue | 1 |
| Pages | 33-49 |
| Publication date | 2002-01-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Human Biology (JOURNAL) |
| Journal identifiers | ISSN: 0018-7143 • E-ISSN: 1534-6617 |
| Publisher | Project MUSE (PUBLISHER • US) |
| DOI | 10.1353/hub.2002.0002 |
| PMID | 11931578 |
| OpenAlex | W2091479169 |
| Language | EN |
| Citations received | 11 |
| References cited | 21 |
Genetic diversity at the nine short tandem repeat (STR) loci, which are universally approved and widely used for forensic investigations, has been studied among nine Indian populations with diverse ethnic, linguistic, and geographic backgrounds. The nine STR loci were profiled on 902 individuals using fluorescent detection methods on an ABI377 System, with the aid of an Amp-F1 Profiler Plus Kit. The studied populations include two upper castes, Brahmin and Kayastha; a tribe, Garo, from West Bengal; a Hindu caste, Meitei, with historical links to Bengal Brahmins; a migrant group of Muslims; three tribal groups, Naga, Kuki and Hmar, from Manipur in northeast India; and a middle-ranking caste, Golla, who are seminomadic herders from Andhra Pradesh. Gene diversity analysis suggests that the average heterozygosity is uniformly high (>0.8) in the studied populations, with the coefficient of gene differentiation at 0.050 +/- 0.0054. Both neighbor-joining (NJ) and unweighted pair group method with arithmetic mean (UPGMA) trees based on DA distances bring out distinct clusters that are consistent with ethnic, linguistic, and/or geographic backgrounds of the populations. The fit of the Harpending and Ward model of regression of average heterozygosity on the gene frequency centroid is found to be good, and the observed outliers are consistent with the population structure and history of the studied populations. Our study suggests that the nine STR loci, used so far mostly for forensic investigations, can be used fruitfully for microevolutionary studies as well, and for reconstructing the phylogenetic history of human populations, at least at the local level
Allele · Biology · Caste · Evolutionary biology · Gene · Genetic diversity · Geography · Linguistics · Loss of heterozygosity · Microsatellite · Population · Sociology · UPGMA · Demography · Forensic and Genetic Research · Genetic diversity and population structure · Genetics · Yersinia bacterium, plague, ectoparasites research
Genetic heterogeneity in northeastern India
Molecular Genetic Perspectives on the Origin of the Lyngngam Tribe of Meghalaya, India
Antiquity, geographic contiguity and genetic affinity among Tibeto-Burman populations of India
Genetic Heterogeneity Among Three Adi Tribes of Arunachal Pradesh, India
Microsatellite Diversity among Three Endogamous Tamil Populations Suggests Their Origin from a Separate Dravidian Genetic Pool
Population Genetic Analysis among Five Indian Population Groups Using Six Microsatellite Markers
Microsatellite Diversity in Andhra Pradesh, India
Minimal Sharing of Y-Chromosome STR Haplotypes Among Five Endogamous Population Groups from Western and Southwestern India
Patterns of Ethnic, Linguistic, and Geographic Heterogeneity of Palmar Interdigital Ridge Counts in the Indian Subcontinent
Effect of Sociocultural Cleavage on Genetic Differentiation
Genetic Diversity and Relationships among the Tribes of Meghalaya Compared to Other Indian and Continental Populations
Accuracy of estimated phylogenetic trees from molecular data
Performing the Exact Test of Hardy-Weinberg Proportion for Multiple Alleles
Multiple origins of the mtDNA 9-bp deletion in populations of South India
Genetic variation observed at three tetrameric short tandem repeat loci HumTHO1, TPOX, and CSF1PO? in five ethnic population groups of northeastern India
Genetic studies among the Nagas and Hmars of eastern India
Population Substructure and Patterns of Quantitative Variation among the Gollas of Southern Andhra Pradesh, India
Genomic Diversity at Thirteen Short Tandem Repeat Loci in a Substructured Caste Population, Golla, of Southern Andhra Pradesh, India
R -Matrix Analysis and Patterns of Gene Flow in India
| Unique citing works | 11 |
|---|---|
| Citations per year | 0,48 |
| Citation span | 2003 - 2012 (10) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 11 |