D1S80 Single-Locus Discrimination Among African Populations

Datos Bibliográficos

ID6068352
AutoresRene J Herrera (0000-0002-5119-4381, Florida International University), Leslie R Adrien, Luis M Ruiz, Nahir Y Sanabria, George Duncan, George T Duncan (0000-0002-4931-5316)
Año2004
Volumen76
Número1
Páginas87-108
Fecha de publicación2004-01-01
Peer ReviewedSí
Open AccessNo
TipoARTICLE
RevistaHuman Biology (JOURNAL)
Identificadores de la revistaISSN: 0018-7143 • E-ISSN: 1534-6617
EditorialProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2004.0022
PMID15222682
OpenAlexW2043663804
IdiomaEN
Citas recibidas7
Referencias citadas9

The highly polymorphic D1S80 locus has no known genetic function. However, this variable number of tandem repeats (VNTR) locus has been highly valuable in forensic identification. In this study we report the allele and genotype frequencies of five African populations (Benin, Cameroon, Egypt, Kenya, and Rwanda), which can be used as databases to help characterize populations and identify individuals. The allele frequencies were used to infer genetic associations through phylogenetic, principal component, and G test statistical analyses. Compliance with Hardy-Weinberg equilibrium expectations was determined as were F(ST) estimates, theta p values, and power of discrimination assessment for each population. Our analyses of 28 additional populations demonstrate that the D1S80 locus alone can be used to discriminate geographic and ethnic groups. We have generated databases useful for human identification and phylogenetic studies

Allele · Allele frequency · Biology · Evolutionary biology · Gene · Genotype · Locus (genetics) · Phylogenetic tree · Population · Variable number tandem repeat · Demography · Forensic and Genetic Research · Genetic diversity and population structure · Genetics · Identification and Quantification in Food