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Minimal hierarchical analysis of global human Y-chromosome SNP diversity by PCR-RFLP

Bibliographic Data

ID6135850
AuthorsMurray P Cox (0000-0003-1936-0236, Arizona Research Laboratories-Biotechnology, University of Arizona, corresponding author)
Year2006
Volume114
Issue1
Pages69-74
Publication date2006-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnthropological Science (JOURNAL)
Journal identifiersISSN: 0918-7960 • E-ISSN: 1348-8570
PublisherAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.050712
OpenAlexW2031066639
LanguageEN
Citations received2
References cited28

Phylogenetically informative binary polymorphisms on the Y-chromosome have become a standard source of markers for molecular anthropology studies. Although several analytical methods are currently available, most methodologies rely on specialized equipment or expensive reagents that research groups with a primarily anthropological focus often cannot afford. Here I present 15 Y-chromosome lineage assays based on a more widely accessible technique—Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). In conjunction with eight pre-existing tests, these validated protocols allow the assignment of unknown men to every major branch of the global Y-chromosome tree, including the 18 haplogroups/paragroups defined by the Y-Chromosome Consortium. While not intended to supplant the high-throughput technologies adopted by advanced research units, these minimal protocols will allow smaller molecular anthropology groups to survey male variation in a broader range of human populations, thereby furthering our understanding of global human Y-chromosome diversity

Allele · Biology · Chromosome · Computational biology · Evolutionary biology · Gene · Haplogroup · Haplotype · Lineage (genetic · Polymerase chain reaction · Restriction fragment length polymorphism · Y chromosome · Forensic and Genetic Research · Genetic diversity and population structure · Race, Genetics, and Society · Genetics

  • Y‐chromosome diversity is inversely associated with language affiliation in paired Austronesian‐ and Papuan‐speaking communities from Solomon Islands

    Open Access•Murray P Cox, M M Lahr•American Journal of Human Biology•2006

  • Y chromosome diversity among the Iranian religious groups

    Open Access•Zahra Lashgary, Ahmad Khodadadi et al.•Annals of Human Biology•2011

  • The human Y chromosome

    Open Access•Mark A Jobling, Chris Tyler‐smith et al.•Nature Reviews Genetics•2003

  • Y chromosome sequence variation and the history of human populations

    Open Access•Peter A Underhill, Peidong Shen et al.•Nature Genetics•2000

  • Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather than by Language

    Open Access•Zoë H Rosser, Tatiana Zerjal et al.•The American Journal of Human…•2000

  • High-Resolution SNPs and Microsatellite Haplotypes Point to a Single, Recent Entry of Native American Y Chromosomes into the Americas

    Open Access•Stephen L Zegura•Molecular Biology and Evolution•2003

  • The phylogeography of Y chromosome binary haplotypes and the origins of modern human populations

    Open Access•P A Underhill, Giuseppe Passarino et al.•Annals of Human Genetics•2001

  • Independent Origins of Indian Caste and Tribal Paternal Lineages

    Open Access•R Cordaux•Current Biology•2004

  • Y‐chromosome diversity is inversely associated with language affiliation in paired Austronesian‐ and Papuan‐speaking communities from Solomon Islands

    Open Access•Murray P Cox, M M Lahr•American Journal of Human Biology•2006

  • Balinese Y-Chromosome Perspective on the Peopling of Indonesia

    Tatiana M Karafet, J S Lansing et al.•Human Biology•2005

Unique citing works2
Citations per year0,1
Citation span2006 - 2011 (6)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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