Changes in physical activity 1 year after breast cancer diagnosis and associations with patient-reported outcomes

Results from the Amber cohort

Bibliographic Data

ID7146790
AuthorsJeff Vallance, Jeff K Vallance (0000-0003-1135-8772, Athabasca University), Christine Friedenreich, Christine M Friedenreich (0000-0002-4783-1966, Alberta Health Services), Ruixuan Zhang (0009-0009-2452-884X, Alberta Health Services), Qinggang Wang (0000-0002-3975-1560, Alberta Health Services), Charles Matthews (0000-0001-8037-3103, National Cancer Institute), Lin Yang (0000-0002-1698-6666, Alberta Health Services), Margaret Mcneely (0000-0003-4376-4847, University of Alberta), Chad Wagoner, Chad W Wagoner (0000-0002-4930-4238, Knoxville College), Nicole Culos-Reed (0000-0003-3896-7383, University of Calgary), Gordon Bell (0000-0003-1884-0924, University of Alberta), Jessica Mcneil (0000-0002-1078-5812, University of North Carolina at Greensboro), Leanne Dickau (Alberta Health Services), Kerry S Courneya (0000-0002-9677-3918, University of Alberta), Kerry Courneya
Year2025
Volume59
Issue1
Publication date2025-01-04
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnnals of Behavioral Medicine (JOURNAL)
Journal identifiersISSN: 0883-6612 • E-ISSN: 1532-4796
PublisherOxford University Press (PUBLISHER • GB)
DOI10.1093/abm/kaaf098
PMID41350111
OpenAlexW4417091258
LanguageEN
References cited36

BACKGROUND: Few studies have prospectively examined how changes in physical activity in the first year after a breast cancer diagnosis may affect patient-reported outcomes (PROs) including quality of life and fatigue. PURPOSE: The purpose of this study was to examine changes in device-measured physical activity and associations with changes in quality of life [physical composite summary score (PCS) and mental composite summary score (MCS)] and fatigue from the first year after diagnosis among newly diagnosed women with breast cancer in the Alberta Moving Beyond Breast Cancer Study. METHODS: In this prospective cohort study, we assessed women within a median of 60 days postsurgery (N = 1442) and again 1 year later (N = 1194). At both timepoints, participants wore an ActiGraph accelerometer for 7 days to measure light and moderate-to-vigorous physical activity (MVPA) and an activPAL accelerometer for daily steps. We used analysis of covariance to compare PRO change scores (dependent variables: PCS and MCS, and fatigue) across activity change quartiles (Q). RESULTS: Participants were categorized into Q1 (decreased activity: mean changes = -37.2 minutes/day), Q2 (stable activity: mean change = -4.8 minutes/day), Q3 (modest increase in activity: mean change = 13.2 minutes/day), and Q4 (large increase in activity: mean change = +49.8 minutes/day). For MVPA, participants in Q4 had significantly larger improvements in PCS and MCS compared with those in the lowest quartiles (PCS: Q1 Δ = 1.5 points, P = .026; Q2 Δ = 1.6 points, P = .017; MCS: Q1 Δ = 2.2 points, P = .007). Significant differences also emerged for fatigue as participants in Q4 of MVPA reported improvements in fatigue compared to those in Q1 (Δ = 1.9 points, P = .017) and Q2 (Δ = 1.9 points, P = .016). Improvements in PCS, MCS, and fatigue were observed when comparing the highest quartile of change (Q4) in light intensity activity, daily steps, and MVPA in ≥10-minute bouts to those in Q1 and Q2. CONCLUSIONS: Women with breast cancer who increased physical activity from diagnosis to 1 year had significantly better improvements in PCS, MCS, and fatigue compared with those who decreased or maintained their physical activity.

Breast cancer · Cohort · Cohort study · Motor activity · Physical activity · Physical activity level · Cancer Risks and Factors · Cancer survivorship and care · Physical Activity and Health

Tools

Open DOIOpen Access