Expression of Uchl1 in the Dental Epithelium during Mouse Tooth Development
Bibliographic Data
| ID | 7198371 |
|---|---|
| Authors | Hyang Seok Kim (Jeonbuk National University), Dong Won Kim (0000-0001-8624-0168, Jeonbuk National University), Jin Young Yang (0000-0002-5515-2875, Jeonbuk National University), Eun Ha Jang (Jeonbuk National University), Tak Heun Kim (Jeonbuk National University), Eui Sic Cho (Jeonbuk National University) |
| Year | 2007 |
| Volume | 20 |
| Issue | 3 |
| Pages | 235-235 |
| Publication date | 2007-01-01 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Korean Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 1225-150X • E-ISSN: 2287-626X |
| Publisher | Korean Association of Physical Anthropologists (PUBLISHER) |
| DOI | 10.11637/kjpa.2007.20.3.235 |
| OpenAlex | W2119675696 |
| Language | EN |
| References cited | 1 |
Tooth is formed by the reciprocal interactions between the ectoderm and ectomesenchyme derived from neural crest. It has not been clear that neuronal factors involved in the morphogenesis and differentiation of tooth. To identify the roles of neuronal factors during the tooth development, the expression patterns and localization of Uchl1 were investigated in the developing mouse tooth germ by in situ hybridization and immunohistochemistry. Uchl1 transcripts were weakly expressed in the oral epithelium and dental lamina at bud stage. However, expression of Uchl1 was not found in the oral epithelium from cap stage and observed in the inner enamel epithelium, stellate reticulum and dental papilla. From the bell stage, Uchl1 was expressed in the inner enamel epithelium and ameloblasts. Uchl1, was appeared to be localized in the inner enamel epithelium and differentiating ameloblasts of molar and incisors at neonates. Uchl1 was localized strongly in the fully differentiated ameloblasts and adjacent papillary layer whereas localized weakly in the odontoblasts of the molar at postnatal day 5. From these results, Uchl1 was expressed and localized in the differentiating dental epithelium and ameloblasts during tooth development. The results suggest that neuronal protein, Uchl1 may play roles in the histo- and cyto-differentiation of non-neuronal dental epithelium
Biology · Epithelium · Expression (computer science · Cancer-related gene regulation · Computer Science · dental development and anomalies · Dentistry · Medicine · Cell Biology · Genetics
| Highly cited | No |
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