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Comparative Study of Genetic Variation at 15 STR Loci in Three Isolated Populations of the Bosnian Mountain Area

Bibliographic Data

ID7990413
AuthorsDamir Marjanović (0000-0002-7472-4525, Institute of Metrology of Bosnia and Herzegovina), Lejla Kapur, Katja Drobnić, Bruce Budowle (0000-0003-4116-2930), Naris Pojskic (0000-0001-6765-2976), Rifat Hadziselimović (0000-0002-6590-8824)
Year2004
Volume76
Issue1
Pages15-31
Publication date2004-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueHuman Biology (JOURNAL)
Journal identifiersISSN: 0018-7143 • E-ISSN: 1534-6617
PublisherProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2004.0024
PMID15222678
OpenAlexW2161728965
LanguageEN
Citations received5
References cited11

Fifteen autosomal STR loci (D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, VWA, D8S1179, TPOX, and FGA) were studied in three geographically close but isolated populations from the Bosnian mountain area. The three villages are Bobovica, Dejcici, and Lukomir. DNA was obtained from 83 individuals, and the allele frequencies and genetic diversity among the three sample groups were compared. In addition, seven of the STR loci (CSF1PO, D13S317, D3S1358, D5S818, D7S820, FGA, TH01) were used in a comparative population analysis of the Bjelasnica-Treskavica region and the Adriatic islands of Brac, Hvar, and Korcula. Although the sample sizes are relatively small, the observed variation within any of the small isolated populations is high and comparable to less isolated groups. In addition, even though the populations are geographically isolated, the STR data are similar among the populations. The most significant frequency differences were observed at the TH01 locus. Although the specific allele distributions in any untyped population cannot be determined a priori, we find support for a high degree of diversity for the STR loci in most populations. In addition, the multiple locus profile is highly informative not only for various population studies but also for forensic studies, even when specific population data are not available

Allele · Allele frequency · Biology · Evolutionary biology · Gene · Genetic diversity · Genetic variation · Locus (genetics · Population · Population genetics · Demography · Forensic and Genetic Research · Genetics · Identification and Quantification in Food · Molecular Biology Techniques and Applications

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Unique citing works5
Citations per year0,24
Citation span2005 - 2021 (17)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 5

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