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Genetic Variation at Nine Short Tandem Repeat Loci Among Islanders of the Eastern Adriatic Coast of Croatia

Bibliographic Data

ID7990422
AuthorsIrena Martinović Klarić (0000-0002-6545-5589, Institute for Anthropological Research), Marijana Peričić, Lovorka Barać Lauc, Branka Janićijević (0000-0002-2466-4392), Milovan Kubat, Dino Pavičić, Igor Rudan (0000-0001-6993-6884), Ning Wang (0009-0007-8931-918X), Li Jin (0000-0001-9201-2321), Lin Jin (0000-0002-5114-7139), Ranajit Chakraborty (0000-0001-9576-916X), Ranjan Deka (0000-0003-2680-1159), Pavao Rudan
Year2005
Volume77
Issue4
Pages471-486
Publication date2005-01-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueHuman Biology (JOURNAL)
Journal identifiersISSN: 0018-7143 • E-ISSN: 1534-6617
PublisherProject MUSE (PUBLISHER • US)
DOI10.1353/hub.2005.0065
PMID16485777
OpenAlexW2072957960
LanguageEN
References cited7

We have analyzed the extent of genetic variation at nine autosomal short tandem repeat loci (D3S1358, VWA, FGA, TH01, TPOX, CSF1PO, D5S818, D13S317, D7S820) among six populations from Croatia: five distributed in the islands of the eastern Adriatic coast and one from the mainland. The purpose is to investigate the usefulness of these loci in detecting regional genetic differentiation in the studied populations. Significant heterogeneity among the island and mainland populations is revealed in the distributions of allele frequencies; however, the absolute magnitude of the coefficient of gene differentiation is small but significant. The summary measures of genetic variation, namely, heterozygosity, number of alleles, and allele size variance, do not indicate reduced genetic variation in the island populations compared to the mainland population. In contrast to the two measures of genetic variation, allele size variance and within-locus heterozygosity, the imbalance index (beta) indicates evidence of recent expansion of population sizes in all islands and in the mainland. High mutation rates of the studied loci together with local drift effects are likely explanations for interisland genetic variation and the observed lack of reduced genetic diversity among the island populations

Allele · Allele frequency · Biology · Evolutionary biology · Gene · Genetic diversity · Genetic drift · Genetic variation · Locus (genetics · Loss of heterozygosity · Mainland · Microsatellite · Population · Demography · Ecology · Forensic and Genetic Research · Genetic Associations and Epidemiology · Genetic diversity and population structure · Genetics

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Citation velocityhistorical
Highly citedNo

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