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Diagnosing congenital syphilis using H utchinson's method

Differentiating between syphilitic, mercurial, and syphilitic‐mercurial dental defects

Bibliographic Data

ID8311552
AuthorsStella Ioannou (0000-0003-2042-302X, Biological Anthropology and Comparative Anatomy Research Unit, School of Medicine, The University of Adelaide South Australia 5005 Australia, corresponding author), Sadaf Sassani (Biological Anthropology and Comparative Anatomy Research Unit, School of Medicine, The University of Adelaide South Australia 5005 Australia), M Henneberg (0000-0003-1941-2286, Biological Anthropology and Comparative Anatomy Research Unit, School of Medicine, The University of Adelaide South Australia 5005 Australia), Renata Henneberg (University of South Australia), Renata J Henneberg (Biological Anthropology and Comparative Anatomy Research Unit, School of Medicine, The University of Adelaide South Australia 5005 Australia)
Year2016
Volume159
Issue4
Pages617-629
Publication date2016-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.22924
PMID26696588
OpenAlexW2210399189
LanguageEN
Citations received13
References cited70

OBJECTIVES: This study focuses on the dental abnormalities observed by Sir Jonathan Hutchinson, Henry Moon and Alfred Fournier in patients with congenital syphilis and in those treated with mercury, in order to define alterations in dental morphology attributable to each of these causes. These definitions are applied to reported paleopathological cases, exploring various etiologies behind the defects, in order to aid in the diagnosis of congenital syphilis. METHODS: Original works were examined for descriptions of dental abnormalities in congenital syphilis and in mercurial treatments. These descriptions were compared with dentitions of paleopathological cases (n = 4) demonstrating abnormalities attributed to congenital syphilis. RESULTS: Distinct morphological differences were recognized between congenital syphilitic teeth and teeth affected by mercury. Mercury produces a pronounced deficiency in enamel of incisors, canines and first permanent molars that become rugged and pitted, and of dirty grey honeycombed appearance. Mercury-induced dental changes are evident in three out of four cases studied here. In one case, only syphilitic changes were present. DISCUSSION: Dental changes in congenital syphilis range from no visible signs to those beyond the classical models of Hutchinson, Moon and Fournier. Treatment of neonates and infants with mercury produces additional changes. Signs of disease and treatment with mercury on teeth may occur together; permanent incisors, first molars and canines, are typically affected, premolars and second/third molars are usually spared. Signs of treatment with mercury might be the only evidence of the occurrence of the disease as mercury was rarely used to treat other diseases

Congenital syphilis · Enamel paint · Etiology · Human immunodeficiency virus (HIV) · Mercury (programming language) · Molar · Pathology · Syphilis · dental development and anomalies · Dentistry · Dermatology · Forensic Anthropology and Bioarchaeology Studies · Immunology · Medicine · Syphilis Diagnosis and Treatment

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Unique citing works13
Citations per year1,3
Citation span2016 - 2023 (8)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 11
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