Association between ancient bone preservation and dna yield
A multidisciplinary approach
Dados Bibliográficos
Ancient molecular typing depends on DNA survival in archaeological bones. Finding valuable tools to predict DNA presence in ancient samples, which can be measured prior to undertaking a genetic study, has become an important issue as a consequence of the peculiarities of archaeological samples. Since the survival of DNA is explained by complex interrelations of multiple variables, the aim of the present study was to analyze morphological, structural, chemical, and biological aspects of a set of medieval human bones, to provide an accurate reflection of the state of preservation of the bony components and to relate it with DNA presence. Archaeological bones that yielded amplifiable DNA presented high collagen content (generally more than 12%), low racemization values of aspartic acid (lesser than 0.08), leucine and glutamic acid, low infrared splitting factor, small size of crystallite, and more compact appearance of bone in the scanning electron micrographs. Whether these patterns are characteristic of ancient bones or specific of each burial site or specimen requires further investigation. Am J Phys Anthropol 151:102–109, 2013. © 2013 Wiley Periodicals, Inc
Ancient DNA · Archaeology · Biology · DNA · Evolutionary biology · Mineralogy · Yield (engineering) · Archaeology and ancient environmental studies · Biochemistry · Chemistry · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · History · Materials Science · Medicine
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Diagenesis of archaeological bone and tooth
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An FTIR-based model for the diagenetic alteration of archaeological bones
Machine learning ATR-FTIR spectroscopy data for the screening of collagen for ZooMS analysis and mtDNA in archaeological bone
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Immaculate conceptions
Methodological strategies to assess the degree of bone preservation for ancient DNA studies
ATR-FTIR spectroscopy as a pre-screening technique for the PMI assessment and DNA preservation in human skeletal remains – A review
Stable Isotope and Radiocarbon Dating of the Remains of the Medieval Royal House of Aragon (Spain) Shed Light on Their Diets, Life Histories and Identities
Ancient human genomics
Ancient DNA extraction from bones and teeth
The survival of organic matter in bone
Infant taphonomy
Collagen Extraction from Recent and Fossil Bones
Amino acids in archaeological bone
Amino acids in archaeological bone (2)
States of preservation of bones from prehistoric sites in the Near East
Aspartic acid racemization variability in ancient human remains
A Basic Mathematical Simulation of the Chemical Degradation of Ancient Collagen
Measurements and Relationships of Diagenetic Alteration of Bone from Three Archaeological Sites
Intcal04 Terrestrial Radiocarbon Age Calibration, 0–26 Cal Kyr BP
Characterization and dating of recent and fossil bone by X-ray diffraction
New parameters for the characterization of diagenetic alterations and heat-induced changes of fossil bone mineral using Fourier transform infrared spectrometry
Patterns of Diagenesis in Bone I
Towards High-Precision AMS
Improvements to the Pretreatment of Bone at Oxford
Bone diagenesis
The long–term survival of bone
Bone preservation and DNA amplification
Radiocarbon Dates from the Oxford Ams System
The thermal history of human fossils and the likelihood of successful DNA amplification
Amino acid composition of degraded matrix collagen from archaeological human bone
| Obras citantes distintas | 16 |
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| Citações por ano | 1,33 |
| Intervalo de citações | 2014 - 2025 (12) |
| Velocidade de citação | recent |
| Altamente citado | Não |
| Tipos de citação | Neutras: 15 |