Tyrosinase positive oculocutaneous albinism among the Zuni and the Brandywine triracial isolate
Biochemical and clinical characteristics and fertility
Bibliographic Data
| ID | 8315635 |
|---|---|
| Authors | Carl J Witkop (University of Minnesota Medical Center), Jerry D Niswander (National Institutes of Health), Donald R Bergsma (National Institutes of Health), PETER L WORKMAN, James G White (0009-0006-0586-9532, University of Minnesota Medical Center) |
| Year | 1972 |
| Volume | 36 |
| Issue | 3 |
| Pages | 397-405 |
| Publication date | 1972-05-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330360311 |
| PMID | 4624656 |
| OpenAlex | W2070467926 |
| Language | EN |
| Citations received | 6 |
| References cited | 6 |
Zuni albinos develop increased pigmentation in hair and eyes, and decreased nystagmus and photophobia with age. Hair bulbs cultured in l‐tyrosine produced pigment. Ultrastructure of melanocytes demonstrated a predominance of Stage II and early Stage III premelanosomes that readily converted to mature Stage IV melanosomes after incubation in 1‐tyrosine. Eleven obligate heterozygotes failed to demonstrate diaphanous irides. Data on the fertility of Zuni and Brandywine male albinos did not indicate that they had more offspring than pigmented males. As the physical features of this form of albinism overlap those of many normal Caucasians, it is probably not a particularly deleterious trait with high selective value under the recent conditions of Zuni life
Albinism · Biology · Botany · Fertility · Melanin · Melanosome · Obligate · Oculocutaneous albinism · Offspring · Photophobia · Plumage · Population · Pregnancy · Tyrosinase · Zoology · Biochemical Analysis and Sensing Techniques · Biochemistry · Genetics · Medicine · melanin and skin pigmentation · Physiology · Skin Protection and Aging
| Unique citing works | 6 |
|---|---|
| Citations per year | 0,12 |
| Citation span | 1974 - 2022 (49) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 6 |