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Cardiorespiratory characteristics and adaptation to high altitudes

Bibliographic Data

ID8315826
AuthorsRichard B Maze (0000-0001-6647-4311, UW Health University Hospital, corresponding author), Richard B Mazess
Year1970
Volume32
Issue2
Pages267-278
Publication date1970-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330320216
PMID5437838
OpenAlexW2088707424
LanguageEN
Citations received4
References cited52

The lowered partial pressure of oxygen at high altitude is one of the severest and most pervasive environmental stresses affecting human populations. Virtually all organ systems and physiological functions are affected by hypoxia, and only elaborate modern technology can temporarily ameliorate the hypoxic stress of altitude exposure. The biological and behavioral responses of newcomers, sojourners, and native residents at higher elevations could provide a paradigm of the study of man's adaptation to the physical environment. Cardiorespiratory characteristics are closely related to altitude exposure, and certain alterations in these characteristics constitute the principal adaptive responses of the organism to hypoxia. However, not all altitude‐related characteristics are beneficial to the organism; some peculiar characteristics occurring at high altitude may be without benefits, or may even be pathological and maladaptive. The roles of age, sex, race, physical condition, nutrition, and intensity and frequency of exposure during growth and development of altitude‐related characteristics are not entirely understood. Moreover the influence of even large circulatory and respiratory alterations, on tissue oxygen tension may be small, and their adaptive significance difficult to evaluate. An equivalent level of functional adaptation might be achieved through differing combinations of structural, functional, and behavioral characteristics. It is concluded that more rigorous evaluations of adaptation to the environment are needed

Adaptation (eye) · Adaptive response · Altitude (triangle) · Biology · Cardiorespiratory fitness · Effects of high altitude on humans · Hypoxia (environmental) · Organism · Oxygen · Oxygen tension · Stressor · Anatomy · Chemistry · Chronic Obstructive Pulmonary Disease (COPD) Research · Ecology · High Altitude and Hypoxia · Neuroscience · Neuroscience of respiration and sleep · Physiology

  • Studies of Modern Man

    D F Roberts, J C Bear•Annual Review of Anthropology•1972

  • The distribution of haemoglobin concentration in a sample of native high-altitude women

    Open Access•G Moreno-Black, Victoria J Quinn et al.•Annals of Human Biology•1984

  • Environmental influences on human growth and development

    Open Access•Lawrence M Schell, Mia V Gallo et al.•Annals of Human Biology•2009

  • Altitude, migration, and fertility in the Andes

    Andrew Abelson, Andrew E Abelson et al.•Social Biology•1974

  • Human Adaptation to High Altitude

    Open Access•Paul T Baker•Science•1969

  • The oxygen cost of breathing in man

    Open Access•Richard B Maze, Richard B Mazess•American Journal of Physical…•1968

  • Respiratory adaptation in the Indian natives of the peruvian andes. Studies at high altitude

    Open Access•Alberto Hurtado•American Journal of Physical…•1932

Unique citing works4
Citations per year0,07
Citation span1972 - 2009 (38)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 3

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