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Experimental radio‐osteonecrosis in Rhesus macaque jaws; therapeutic irradiation dose effect on dental extraction wound healing

Bibliographic Data

ID8316571
AuthorsLeo Zach (United States Department of Veterans Affairs), Gerson Cohen (United States Department of Veterans Affairs), Irwin Scopp, Irwin Walter Scopp (United States Department of Veterans Affairs), Gustave Kaplan (0000-0001-9341-1332, United States Department of Veterans Affairs)
Year1973
Volume38
Issue2
Pages325-330
Publication date1973-03-01
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330380228
PMID4632079
OpenAlexW2088947205
LanguageEN
References cited4

Varying degrees of osteonecrosis result from molar extractions or other oral surgical procedures in rhesus macaques before, during, or after the administration of 6000 rad (the equivalent of human therapeutic dose levels) via either 240 kVp x‐ray or cobalt 60 irradiation to the jaw areas subjected to surgery. The effects of various experimental time‐dose‐wound combinations on the level of impairment of wound‐healing, interruption of osteogenesis, and the nature of the response of the irradiation‐compromised tissues are covered in this report

Dental extraction · Irradiation · Molar · Rhesus macaque · Therapeutic effect · Wound healing · Bone and Joint Diseases · Bone health and treatments · Dentistry · Immunology · Medicine · Oral health in cancer treatment · Surgery

Highly citedNo

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