Interethnic variability in birth weight and genetic background
A study of placental alkaline phosphatase
Bibliographic Data
| ID | 8317199 |
|---|---|
| Authors | A Amante (University of Rome Tor Vergata), Paola Borgiani (0000-0003-0859-4328, University of Rome Tor Vergata), A Gimelfarb (University of Chicago), F Gloria-Bottini, F Gloria‐bottini (University of Rome Tor Vergata, corresponding author) |
| Year | 1996 |
| Volume | 101 |
| Issue | 4 |
| Pages | 449-453 |
| Publication date | 1996-12-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/(sici)1096-8644(199612)101:4<449::aid-ajpa1>3.0.co;2-r |
| PMID | 9016360 |
| OpenAlex | W2088028828 |
| Language | EN |
| Citations received | 2 |
| References cited | 14 |
The relationship between human placental alkaline phosphatase (PLAP) genotype and birth weight is investigated in a sample of white, black and Puerto-Rican new-born infants from New Haven, Connecticut (total 710 subjects). Black and Puerto-Rican infants show a higher incidence of growth retardation and a higher frequency of ALPp*1/*1 genotype as compared to whites. The proportion of newborns with a low birth weight (below the 10th percentile) is lower in infants with ALPp*1/*1 genotype than in those with other PLAP genotypes, especially among non-whites. It is argued that the higher frequency of ALPp*1 allele among non-whites might be, at least in part, a consequence of their adaptation in the past to environmental conditions adverse to optimal intrauterine development.
Alkaline phosphatase · Biology · Enzyme · Obstetrics · Placental alkaline phosphatase · Alkaline Phosphatase Research Studies · Biochemistry · Birth, Development, and Health · Genetics · Medicine · Selenium in Biological Systems
| Citations per year | 0.09 |
|---|---|
| Citation span | 2003 - 2025 (23) |
| Highly cited | No |