Serum androgens and sex hormone binding globulin in obese Pima Indian females

Bibliographic Data

ID8317212
AuthorsFrances E Purifoy (University of New Mexico), Lambert H Koopmans, Ronald W Tatum, RONALD TATUM (University of New Mexico), Darrel M Mayes (Tarzana Treatment Centers)
Year1981
Volume55
Issue4
Pages491-496
Publication date1981-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330550410
PMID7199823
OpenAlexW2135019136
LanguageEN
Citations received2
References cited23

Levels of serum androgens and sex hormone binding globulin (SHBG) were measured in 20 obese Pima Indian females aged 19–44 and compared with those of normal‐weight Caucasians aged 20–46. The Pima exhibited significantly decreased SHBG compared to Caucasians, but a strong effect of age on androgen levels rendered mean comparisons useless. Androstenedione (A) and dehydroepiandrosterone‐sulfate (DHEA‐S) decreased significantly, and testosterone (T) declined slightly with age in the Pima, whereas these androgens showed no significant decreases in Caucasians for this age range. A possible relationship of androgens to the Pima female's propensity for android obesity as well as possible effects of obesity on SHBG, androgens, and aging is discussed

Androgen · Androstenedione · Biology · Dehydroepiandrosterone · Dehydroepiandrosterone sulfate · Free testosterone · Globulin · Hormone · Obesity · Sex hormone-binding globulin · Testosterone (patch) · Endocrinology · Hormonal and reproductive studies · Internal Medicine · Medicine · Ovarian function and disorders · Regulation of Appetite and Obesity

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