Aerobic capacity of P eruvian Q uechua

A test of the developmental adaptation hypothesis

Bibliographic Data

ID8317565
AuthorsMelisa Kiyamu (0000-0002-4269-6822, Departamento de Ciencias Biológicas y Fisiológicas Universidad Peruana Cayetano Heredia Lima Perú, corresponding author), Maria Rivera‐chira (Departamento de Ciencias Biológicas y Fisiológicas Universidad Peruana Cayetano Heredia Lima Perú), María Rivera-Ch (0000-0001-9470-6642), Tom D Brutsaert (0009-0000-5896-0520, Department of Exercise Science Syracuse University Syracuse NY 13210)
Year2015
Volume156
Issue3
Pages363-373
Publication date2015-03-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.22655
PMID25385548
OpenAlexW2146343527
LanguageEN
References cited55

High altitude natives are reported to have outstanding work capacity in spite of the challenge of oxygen transport and delivery in hypoxia. To evaluate the developmental effect of lifelong exposure to hypoxia on aerobic capacity, VO 2peak was measured on two groups of Peruvian Quechua subjects (18–35 years), who differed in their developmental exposure to altitude. Male and female volunteers were recruited in Lima, Peru (150 m), and were divided in two groups, based on their developmental exposure to hypoxia, those: a) Born at sea‐level individuals (BSL), with no developmental exposure to hypoxia ( n = 34) and b) Born at high‐altitude individuals (BHA) with full developmental exposure to hypoxia ( n = 32), but who migrated to sea‐level as adults (>16‐years‐old). Tests were conducted both in normoxia (BP = 750 mm Hg) and normobaric hypoxia at sea‐level (BP = 750 mm Hg, FiO 2 = 0.12, equivalent to 4,449 m), after a 2‐month training period (in order to control for initial differences in physical fitness) at sea‐level. BHA had a significantly higher VO 2peak at hypoxia (40.31 ± 1.0 ml/min/kg) as compared to BSL (35.78 ± 0.96 ml/min/kg, P = 0.001), adjusting for sex. The decrease of VO 2peak at HA relative to SL (ΔVO 2peak ) was not different between groups, controlling for baseline levels (VO 2peak at sea‐level) and sex (BHA = 0.35 ± 0.04 l/min, BSL = 0.44 ± 0.04 l/min; P = 0.12). Forced vital capacity (controlling for height) and the residuals of VO 2peak (controlling for weight) had a significant association in the BHA group only ( r = 0.155; P = 0.031). In sum, results indicate that developmental exposure to altitude constitutes an important factor to determine superior exercise performance. Am J Phys Anthropol 156:363–373, 2015. © 2014 Wiley Periodicals, Inc

Adaptation (eye) · Adipose Tissue and Metabolism · Chemistry · Chronic Obstructive Pulmonary Disease (COPD) Research · High Altitude and Hypoxia · Neuroscience · Psychology