Anthropometric analysis of the face in hypohidrotic ectodermal dysplasia

A family study

Bibliographic Data

ID8318514
AuthorsRichard E Ward (0000-0001-9885-2276, Indiana University – Purdue University Indianapolis), David Bixler (Indiana University – Purdue University Indianapolis)
Year1987
Volume74
Issue4
Pages453-458
Publication date1987-12-01
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.1330740404
PMID3442296
OpenAlexW2017724045
LanguageEN
Citations received2
References cited9

Sixteen individuals with hypohidrotic ectodermal dysplasia (HED) were compared to normal standards as well as to 16 unaffected family members by using a series of 20 anthropometric measurements of the head and face. Individuals with HED were generally smaller than normal controls or their unaffected relatives. However, this size reduction was not uniform. Instead, it was most evident in the anterior‐posterior dimensions of the lower two‐thirds of the face, in facial height, and in the size of the ears, nose, and mouth. A stepwise discriminant function analysis indicated that a function constructed from four variables (depth of the lower face, width of the nose, mandibular arc, and total facial height) could accurately classify 96.7% of the 32 individuals in the combined sample of affected and unaffected individuals. These findings demonstrated that the face of individuals with HED is unique and can be useful in its diagnosis. Additional studies are needed to determine if similar‐though‐less‐pronounced facial abnormalities can be used to detect minimally affected gene carriers of this presumably X‐linked condition

Anthropometry · Ectodermal dysplasia · Face (sociological concept) · Hypohidrotic ectodermal dysplasia · Social science · Sociology · dental development and anomalies · Dermatology · Internal Medicine · Medicine

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