Great apes show highly selective plasma carotenoids and have physiologically high plasma retinyl esters compared to humans
Bibliographic Data
| ID | 8318834 |
|---|---|
| Authors | Ada Lizbeth Garcia (0000-0002-3526-2380, University of Potsdam, corresponding author), Jens Raila (0000-0003-3481-0792, University of Potsdam), Corinna Koebnick (0000-0001-8274-0309, German Institute of Human Nutrition), Klaus Eulenberger (Helios Park-Klinikum Leipzig), Florian J Schweigert, Florian J Schweigert� (0000-0001-7103-2438, University of Potsdam) |
| Year | 2006 |
| Volume | 131 |
| Issue | 2 |
| Pages | 236-242 |
| Publication date | 2006-10-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.20428 |
| PMID | 16552736 |
| OpenAlex | W2152543924 |
| Language | EN |
| References cited | 40 |
Great apes are the closest living relatives of humans. Physiological similarities between great apes and humans provide clues to identify which biological features in humans are primitive or derived from great apes. Vitamin A (VA) and carotenoid metabolism have been only partially studied in great apes, and comparisons between great apes and humans are not available. We aimed to investigate VA and carotenoid intake and plasma concentrations in great apes living in captivity, and to compare them to healthy humans. Dietary intakes of humans (n = 20) and, among the great apes, chimpanzees (n = 15) and orangutans (n = 5) were calculated. Plasma retinol (ROH), retinol-binding protein (RBP), retinyl esters, and major carotenoids were analyzed. The great ape diet was higher in VA than in humans, due to high intake of provitamin A carotenoids. Plasma ROH concentrations in great apes were similar to those in humans, but retinyl esters were higher in great apes than in humans. Differences in plasma carotenoid concentrations were observed between great apes and humans. Lutein was the main carotenoid in great apes, while beta-carotene was the main carotenoid for humans. RBP concentrations did not differ between great apes and humans. The molar ratio of ROH to RBP was close to 1.0 in both great apes and humans. In conclusion, great apes show homeostatic ROH regulation, with high but physiological retinyl esters circulating in plasma. Furthermore, great apes show great selectivity in their plasmatic carotenoid concentration, which is not explained by dietary intake
Carotenoid · Chromatography · Human plasma · Physics · Plasma · Antioxidant Activity and Oxidative Stress · Biochemical Analysis and Sensing Techniques · Biochemistry · Chemistry · Retinoids in leukemia and cellular processes
Western lowland gorilla diet and resource availability
Western gorilla diet
Diet composition of chimpanzees inhabiting the Montane forest of Kahuzi, Democratic Republic of Congo
Observations on effects of neonatal castration upon sexual and aggressive behavior in the male common marmoset ( Callithrix jacchus )
Proteomic comparison of human and great ape blood plasma reveals conserved glycosylation and differences in thyroid hormone metabolism
| Highly cited | No |
|---|