Comparison of radiologic and gross examination for detection of cancer in defleshed skeletons
Bibliographic Data
| ID | 8318943 |
|---|---|
| Authors | Bruce M Rothschild, Bruce Rothschild (0000-0003-1327-6615, University of Akron, corresponding author), Christine Rothschild (University of Akron) |
| Year | 1995 |
| Volume | 96 |
| Issue | 4 |
| Pages | 357-363 |
| Publication date | 1995-04-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330960404 |
| PMID | 7604891 |
| OpenAlex | W2166810286 |
| Language | EN |
| Citations received | 31 |
| References cited | 14 |
The reliability of visual examination of defleshed bones was assessed for detection of postcranial metastatic disease in individuals known to have had cancer. This was compared with standard clinical radiologic techniques. The skeletons of 128 diagnosed cancer patients from an early 20th century autopsied skeletal collection (Hamann‐Todd Collection) were examined. Radiologic examination detected evidence of metastatic disease in 33 individuals, compared to 11 by visual examination of the postcranial skeletons. Four of these cases were detected by both techniques. Blastic lesions were most commonly overlooked on visual examination, because they were localized to trabecular (internal bone) structures. The ilium was the most commonly affected bone, with lytic or blastic lesions detected in 30 of 33 individuals. While the proximal femur was affected in only nine individuals, x‐ray of the proximal femur and ilium detected all individuals with postcranial evidence of metastatic disease. Skeletal distribution of metastases provides no clue to the location of origin or histologic subtype of the cancer. Survey of archeological human remains for metastatic cancer requires radiologic examination. Such skeletal surveys should x‐ray at least the ilia and femora. © 1995 Wiley‐Liss, Inc
Biology · Cancer · Femur · Gross examination · Pathology · Postcrania · Anatomy · Autopsy Techniques and Outcomes · Forensic Anthropology and Bioarchaeology Studies · Internal Medicine · Medicine · Osteomyelitis and Bone Disorders Research · Surgery
Periosteal reaction recognition and specificity assessed by surface microscopy
A case of multiple metastasis in Late Holocene hunter-gatherers from the Argentine Pampean region
The Unidentified Skeletal Collection of Capuchos Cemetery (Santarém) housed at the University of Coimbra
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What was the Prevalence of Malignant Disease in the Past
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Assessing the relative benefits of imaging with plain radiographs and microCT scanning to diagnose cancer in past populations
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A probable case of multiple myeloma from Bronze Age China
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Detection of cancerous lesions in skeletal remains using visual methods and radiographs
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Metastatic carcinoma in a 14th-19th century skeleton from Constância (Portugal)
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A probable case of metastatic carcinoma from the late prehistoric eastern Tennessee River Valley
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Secondary cancer in an Anglo-Saxon female
Metastasizing carcinoma in a medieval skeleton
Hamann‐Todd collection aging studies
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| Unique citing works | 31 |
|---|---|
| Citations per year | 1,03 |
| Citation span | 1996 - 2026 (31) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 27 |