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Probable destructive meningioma in an archaeological adult male skull from Alaska

Bibliographic Data

ID8319166
AuthorsBirna Jónsdóttir (Domus Medica), Donald J Ortner (Smithsonian Institution, corresponding author), B Frohlich (0000-0003-4444-5733, Smithsonian Institution)
Year2003
Volume122
Issue3
Pages232-239
Publication date2003-11-01
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.10285
PMID14533181
OpenAlexW2030811308
LanguageEN
Citations received4
References cited2

Several intracranial pathological conditions can affect the bones of the skull. The most common cause of these conditions is tumor, but infection and other diseases are also known to affect the bones of the skull. Distinguishing between the various causes of intracranial skeletal pathology in archaeological human remains is usually a challenging exercise, and a specific diagnosis will often be impossible. Meningiomas are tumors that arise in arachnoid tissues embedded in the outer layer of the dura. Because of this association, they occur almost exclusively in the skull and vertebral column. Usually meningiomas are slow‐growing tumors that do not metastasize to other organs and tissues of the body. However, rare cases can be malignant and, even when meningiomas are benign, their presence and growth can adversely affect the nervous and vascular supply to other tissues in the skull and vertebral column. Their effect on adjacent bone tissue varies from stimulating bone‐forming lesions to causing highly destructive lesions. A few examples of meningioma have been described in the paleopathological literature. Most of these cases are bone‐stimulating meningiomas. The case presented here is a probable example of a highly destructive meningioma of the skull base, with unilateral extension into the left side of the cranium. This case is compared with a modern clinical case of destructive intracranial meningioma that was documented both radiographically and pathologically. Destructive meningiomas can be confused with other pathological conditions, including benign and malignant tumors. Criteria for differentiating the diagnostic options are reviewed. Am J Phys Anthropol, 2003. © 2003 Wiley‐Liss, Inc

Meningioma · Pathological · Pathology · Skull · Vertebral column · Anatomy · Bone Tumor Diagnosis and Treatments · Medicine · Meningioma and schwannoma management · Neurofibromatosis and Schwannoma Cases

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Citations per year0.25
Citation span2010 - 2022 (13)
Highly citedNo

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