Immunoglobulin (Gm) allotypes in a sample of Canadian Ashkenazic jews

Gm typing on the serum specimens of 507 Ashkenazic Jews (predominantly of Polish‐Russian ancestry) from Toronto, Canada has established the presence of haplotypes Gm 3;5 , Gm 1;21 , Gm 1,2;21 , and Gm 1,17;5 , and the absence of haplotypes Gm 1;13,15,16 , Gm 1;5,6 , and Gm 1;5,6,24 which have been found in other Jewish peoples. It is suggested that Ashkenazic populations have lower frequencies of haplotype Gm 1,17;5 than non‐European Jewish populations, and that some eastern European Jewish populations have acquired the Gm 1;13,15,16 haplotype through gene flow from Central Asia. Thus Jewish populations show differences in the Gm system; many of the differences may be in the direction of similarities to neighbouring non‐Jewish populations

Antibody · Biology · Chromatography · Sample (material) · Blood groups and transfusion · Chemistry · Genetics · Herpesvirus Infections and Treatments · T-cell and B-cell Immunology

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