Exploring Perceived Barriers and Facilitators of PrEP Uptake among Young People in Uganda, Zimbabwe, and South Africa

Dados Bibliográficos

ID8356946
AutoresRichard Muhumuza (0000-0002-9931-7600, Uganda Virus Research Institute), Andrew Sentoogo Ssemata (0000-0003-0060-0842, Uganda Virus Research Institute), Ayoub Kakande (0000-0002-0243-5601, Uganda Virus Research Institute), Nadia Ahmed (0000-0001-5498-6301, Desmond Tutu HIV Foundation), Millicent Atujuna (0000-0003-1287-2634, Desmond Tutu HIV Foundation), Mangxilana Nomvuyo (Desmond Tutu HIV Foundation), Linda-Gail Bekker (0000-0002-0755-4386, Desmond Tutu HIV Foundation), Janan Dietrich (0000-0002-1949-3138, South African Medical Research Council), Janan Janine Dietrich, Gugulethu Tshabalala (0000-0001-8402-543X, University of the Witwatersrand), Stefanie Hornschuh (0000-0002-5505-6488, University of the Witwatersrand), Mamakiri Maluadzi (University of the Witwatersrand), Lynda Chibanda-Stranix (University of Zimbabwe), Teacler Nematadzira (0000-0003-4786-1396, University of Zimbabwe), Helen A Wei (0000-0003-3547-7936, London School of Hygiene & Tropical Medicine), Helen Anne Weiss, Stephen Nash (0000-0003-2086-1740, London School of Hygiene & Tropical Medicine), Julie Fox (0000-0002-0583-8019, King's College London), Janet Seeley (0000-0002-0583-5272, London School of Hygiene & Tropical Medicine, autor correspondente)
Ano2021
Volume50
Fascículo4
Páginas1729-1742
Data de publicação2021-05-01
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoArchives of Sexual Behavior (JOURNAL)
Identificadores do periódicoISSN: 0004-0002 • E-ISSN: 1573-2800
EditoraSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s10508-020-01880-y
PMID33954824
OpenAlexW3159945523
IdiomaEN
Citações recebidas70
Referências citadas36

Pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy. Few studies have explored adolescents and young people’s perspectives toward PrEP. We conducted 24 group discussions and 60 in-depth interviews with males and females aged 13–24 years in Uganda, Zimbabwe, and South Africa between September 2018 and February 2019. We used the framework approach to generate themes and key concepts for analysis following the social ecological model. Young people expressed a willingness to use PrEP and identified potential barriers and facilitators of PrEP uptake. Barriers included factors at individual (fear of HIV, fear of side effects, and PrEP characteristics), interpersonal (parental influence, absence of a sexual partner), community (peer influence, social stigma), institutional (long waiting times at clinics, attitudes of health workers), and structural (cost of PrEP and mode of administration, accessibility concerns) levels. Facilitators included factors at individual (high HIV risk perception and preventing HIV/desire to remain HIV negative), interpersonal (peer influence, social support and care for PrEP uptake), community (adequate PrEP information and sensitization, evidence of PrEP efficacy and safety), institutional (convenient and responsive services, provision of appropriate and sufficiently resourced services), and structural (access and availability of PrEP, cost of PrEP) levels. The findings indicated that PrEP is an acceptable HIV prevention method. PrEP uptake is linked to personal and environmental factors that need to be considered for successful PrEP roll-out. Multi-level interventions needed to promote PrEP uptake should consider the social and structural drivers and focus on ways that can inspire PrEP uptake and limit the barriers

Family medicine · Focus group · Human immunodeficiency virus (HIV) · Interpersonal communication · Men who have sex with men · Pre-exposure prophylaxis · Psychiatry · Psychological intervention · Social stigma · Sociology · Stigma (botany) · Adolescent Sexual and Reproductive Health · HIV/AIDS Research and Interventions · Medicine · Nursing · Psychology · Sex work and related issues · Social Psychology