Patients’ Accounts of Increased “Connectedness” and “Acceptance” After Psilocybin for Treatment-Resistant Depression
Bibliographic Data
| ID | 9022326 |
|---|---|
| Authors | Rosalind Watts (Imperial College London, London, UK, corresponding author), Camilla Day (Imperial College London, London, UK), Jacob Krzanowski (0000-0001-7749-5716, Imperial College London, London, UK), David Nutt (0000-0002-6423-9411, Imperial College London, London, UK), Robin Carhart-Harris (Imperial College London, London, UK), Robin Carhart‐Harris (Imperial College London) |
| Year | 2017 |
| Volume | 57 |
| Issue | 5 |
| Pages | 520-564 |
| Publication date | 2017-06-19 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Humanistic Psychology (JOURNAL) |
| Journal identifiers | ISSN: 0022-1678 • E-ISSN: 1552-650X |
| Publisher | SAGE Publishing (PUBLISHER • US) |
| DOI | 10.1177/0022167817709585 |
| OpenAlex | W2644260506 |
| Language | EN |
| Citations received | 130 |
| References cited | 41 |
Objective: To identify patients’ perceptions of the value of psilocybin as a treatment for depression. Method: Twenty patients enrolled in an open-label trial of psilocybin for treatment-resistant depression participated in a semistructured interview at 6-month follow-up. Thematic analysis was used to identify patients’ experiences of the treatment and how it compared with previous treatments. Results: Two main change processes were identified in relation to the treatment. The first concerned change from disconnection (from self, others, and world) to connection, and the second concerned change from avoidance (of emotion) to acceptance. A third theme concerned comparison between psilocybin and conventional treatments. Patients reported that medications and some short-term talking therapies tended to reinforce their sense of disconnection and avoidance, whereas treatment with psilocybin encouraged connection and acceptance. Conclusions: These results suggest that psilocybin treatment for depression may work via paradigmatically novel means, antithetical to antidepressant medications, and some short-term talking therapies
Antidepressant · Cognition · Depression (economics · Depressive symptoms · Disconnection · Hallucinogen · Perception · Psilocybin · Psychiatry · Psychotherapist · Chemical synthesis and alkaloids · Clinical Psychology · Complementary and Alternative Medicine Studies · Psychedelics and Drug Studies · Psychology
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| Unique citing works | 130 |
|---|---|
| Citations per year | 16,25 |
| Citation span | 2018 - 2026 (9) |
| Citation velocity | current |
| Highly cited | Yes |
| Citation types | Neutral: 128 |