A Festschrift in Honor of Halsted R. Holman, MD

Hospital in New York. In Dr. Henry Kunkel's lab at Rockefeller Institute, Hal Holman identified antinuclear and antiDNA antibodies that, along with Hargreaves's description of the lupus cell, provided the first evidence of autoimmunity, contrary to the dictum of Paul Ehrlich that autoimmunity was impossible. With his Rockefeller Institute colleague Jules Hirsch, Halsted lectured in schools and church basements about the perils of the nuclear arms race. In 1959, despite his politics and young age of 35 years, he was recruited to build the new Department of Medicine at Stanford after its move from San Francisco to Palo Alto. As chairman, Hal built a new faculty with established leaders, such as Nobel laureates Joshua Lederberg and Arthur Kornberg, and promising young medical scientists. He remarked that his goal as department chairman was to allow the faculty to spend 90% of their time in the laboratory and 10% in patient care. This formula was a success, and Stanford and the Department of Medicine evolved from a reputable clinical school to one of the world's preeminent research and clinical institutions. Holman was a

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