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Two Pharmacy Interventions to Improve Refill Persistence for Chronic Disease Medications

A Randomized, Controlled Trial

Bibliographic Data

ID9099241
AuthorsPaul J Nietert (0000-0002-3933-4986, Medical University of South Carolina, corresponding author), Barbara C Tilley (0000-0002-3952-2282, Medical University of South Carolina, corresponding author), Wenle Zhao (0000-0003-0496-9700, Medical University of South Carolina, corresponding author), Peter Edwards (0000-0002-4527-9186, Medical University of South Carolina), Peter F Edwards, Andrea M Wessell (Medical University of South Carolina), Patrick D Mauldin (0000-0001-8890-4554, Medical University of South Carolina), Pam P Polk (Institute of Refrigeration)
Year2009
Volume47
Issue1
Pages32-40
Publication date2009-01-01
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e3181808c17
PMID19106728
OpenAlexW2013395958
LanguageEN
References cited32

BACKGROUND: Despite the proven effectiveness of many medications for chronic diseases, many patients do not refill their prescriptions in the required timeframe. OBJECTIVE: Compare the effectiveness of 3 pharmacist strategies to decrease time to refill of prescriptions for common chronic diseases. RESEARCH DESIGN/SUBJECTS: A randomized, controlled clinical trial with patients as the unit of randomization. Nine pharmacies within a medium-sized grocery store chain in South Carolina were included, representing urban, suburban, and rural areas and patients from a variety of socioeconomic backgrounds. Patients (n = 3048) overdue for refills for selected medications were randomized into 1 of 3 treatment arms: (1) pharmacist contact with the patient via telephone, (2) pharmacist contact with the patient's prescribing physician via facsimile, and (3) usual care. MEASURES: The primary outcome was the number of days from their recommended refill date until the patient filled a prescription for any medication relevant to his/her chronic disease. Prescription refill data were obtained routinely from the pharmacy district office's centralized database. Patient disposition codes were obtained by pharmacy employees. An intent-to-treat approach was used for all analyses. RESULTS: There were no significant differences by treatment arm in the study outcomes. CONCLUSIONS: Neither of the interventions is more effective than usual care at improving persistence of prescription refills for chronic diseases in overdue patients

Biology · Chronic disease · Family medicine · Intensive care medicine · MEDLINE · Persistence (discontinuity) · Psychiatry · Psychological intervention · Diabetes Management and Education · Medication Adherence and Compliance · Medicine · Pharmaceutical Practices and Patient Outcomes · Pharmacy

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