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Does Exposure to Conflict of Interest Policies in Psychiatry Residency Affect Antidepressant Prescribing

Bibliographic Data

ID9099416
AuthorsAndrew J Epstein (0000-0001-5078-6564, University of Pennsylvania, corresponding author), Susan H Busch (0000-0003-4443-0048), Alisa B Busch (0000-0002-1828-9098, Harvard University), David A Asch (0000-0002-7970-286X, University of Pennsylvania, corresponding author), Colleen L Barry (0000-0001-8211-5036, Johns Hopkins University)
Year2013
Volume51
Issue2
Pages199-203
Publication date2013-02-01
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e318277eb19
PMID23142772
OpenAlexW2034569721
LanguageEN
Citations received4
References cited22

BACKGROUND: Academic medical institutions have instituted conflict of interest (COI) policies in response to concerns about pharmaceutical industry influence. OBJECTIVE: To determine whether exposure to COI policies during psychiatry residency training affects psychiatrists' antidepressant prescribing patterns after graduation. RESEARCH DESIGN: We used 2009 physician-level national administrative prescribing data from IMS Health for 1652 psychiatrists from 162 residency programs. We used difference-in-differences estimation to compare antidepressant prescribing based on graduation before (2001) or after (2008) COI policy adoption across residency program groups with maximally, moderately, and minimally restrictive COI policies. The primary outcomes were shares of psychiatrists' prescribing of heavily promoted, brand reformulated, and brand antidepressants. RESULTS: Rates of prescribing heavily promoted, brand reformulated, and brand antidepressants in 2009 were lower among post-COI graduates than pre-COI graduates at all levels of COI restrictiveness. However, differences between pre-COI and post-COI graduates' prescribing of heavily promoted medications were larger for maximally restrictive programs than both minimally restrictive programs [-4.3 percentage points; 95% confidence interval (CI), -7.0, -1.6] and moderately restrictive programs (-3.6 percentage points; 95% CI, -6.2, -1.1). The difference in prescribing reformulations was larger for maximally restrictive programs than minimally restrictive programs (-3.0 percentage points; 95% CI, -5.3, -0.7). Results were consistent for prescribing of brand drugs. CONCLUSIONS: This study provides the first empirical evidence of the effects of COI policies. Our results suggest that COI policies can help inoculate physicians against persuasive aspects of pharmaceutical promotion. Further research should assess whether these policies affect other drug classes and physician specialties similarly

Affect (linguistics) · Antidepressant · Anxiety · Conflict of interest · Political science · Psychiatry · Healthcare cost, quality, practices · Medicine · Pharmaceutical Economics and Policy · Pharmaceutical industry and healthcare · Psychology

  • Antipsychotic Prescribing

    Timothy S Anderson, Haiden A Huskamp et al.•Medical Care•2015

  • Regulating Pharmaceutical Industry Marketing

    Open Access•Shai Mulinari•Sociology Compass•2016

  • The Scope of Inclusion of Academic Conflict of Interest Policies

    Open Access•Tracy Klein, Janessa M Graves•Journal of Academic Ethics•2017

  • Gifts and influence

    Open Access•Marissa King, P Bearman et al.•Social Science & Medicine•2017

  • Advertising as Information

    Phillip Nelson•Journal of Political Economy•1974

  • The role of commercial sources in the adoption of a new drug

    Open Access•Marilyn Y Peay, Edmund R Peay•Social Science & Medicine•1988

Citations per year0.36
Citation span2015 - 2017 (3)
Highly citedNo

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