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Relative Disutilities of 47 Risk Factors and Conditions Assessed with Seven Preference-Based Health Status Measures in a National U.S. Sample

Toward Consistency in Cost-Effectiveness Analyses

Bibliographic Data

ID9100192
AuthorsPeter Franks (0000-0002-9782-0181, University of California, Davis, corresponding author), Janel Hanmer (0000-0001-6159-2482, University of Wisconsin–Madison), Dennis G Fryback (University of Wisconsin–Madison)
Year2006
Volume44
Issue5
Pages478-485
Publication date2006-05-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/01.mlr.0000207464.61661.05
PMID16641667
OpenAlexW2118178765
LanguageEN
Citations received9
References cited35

BACKGROUND: Preference-based health measures yield summary scores that are compatible with cost-effectiveness analyses. There is limited comparative information, however, about how different measures weight health conditions in the U.S. population. METHODS: We examined data from 11,421 adults in the 2000 Medical Expenditure Panel Survey, a nationally representative sample of the U.S. general population, using information on sociodemographics (age, gender, race/ethnicity, income, and education), health status (EQ-5D, EQ-VAS, and SF-12), 4 risk factors (smoking, overweight, obesity, and lacking health insurance), and 43 conditions. From the EQ-5D, we derived summary scores using U.K. [EQ(UK)] and U.S. weights. From the SF-12 we derived SF-6D, and regression-predicted EQ-5D (U.S. and U.K. weights) and Health Utility Index scores. Each of the 7 preference measures was regressed on each of the 47 problems (risk factors and conditions) to determine the disutility associated with the problem, adjusting for socio-demographics. RESULTS: The adjusted disutilities averaged across the 47 problems for the 7 preference measures ranged from 0.059 for the SF-6D to 0.104 for the EQ(UK). Correlations between each of the measures of the adjusted disutilities ranged from 0.85-1.0. Standardization, using linear regression, attenuated between measure differences in disutilities. CONCLUSIONS: Absolute incremental cost-effectiveness analyses of a given problem would likely vary depending on the measure used, whereas the relative ordering of incremental cost-effectiveness analyses of a series of problems would likely be similar regardless of the measure chosen, as long as the same measure is used in each series of analyses. Absolute consistency across measures may be enhanced by standardization

Body mass index · Economics · Environmental health · EQ-5D · Health care · Health insurance · Linear regression · Medical Expenditure Panel Survey · Overweight · Population · Statistics · Demography · Economic and Environmental Valuation · Health Systems, Economic Evaluations, Quality of Life · Mathematics · Medicine · Nutritional Studies and Diet · Gerontology

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Unique citing works9
Citations per year0,47
Citation span2007 - 2016 (10)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 9

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