Antipsychotic Drug Exposure in a Health Maintenance Organization
Bibliographic Data
| ID | 9102990 |
|---|---|
| Authors | Richard E Johnson (0009-0005-9101-9114, Kaiser Permanente Center for Health Research, corresponding author), Bentson H Mcfarland (0000-0001-9149-5616, Kaiser Permanente Center for Health Research, corresponding author) |
| Year | 1993 |
| Volume | 31 |
| Issue | 5 |
| Pages | 432-444 |
| Publication date | 1993-05-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | Medical Care (JOURNAL) |
| Journal identifiers | ISSN: 0025-7079 • E-ISSN: 1537-1948 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) (PUBLISHER) |
| DOI | 10.1097/00005650-199305000-00005 |
| PMID | 8099137 |
| OpenAlex | W1981392927 |
| Language | EN |
| Citations received | 1 |
| References cited | 7 |
In this study, exposure to antipsychotic drugs among ambulatory health maintenance organization (HMO) members is described. The diagnoses and mental health utilization associated with their use are explored, and concomitant drug use is investigated. The antipsychotic prescriptions were retrieved from an automated outpatient pharmacy data base for 2 years. Diagnoses for a two-percent sample of users were retrieved from an automated outpatient utilization data base. During the 2 years, 1,959 HMO members received 10,361 prescriptions for antipsychotics. Fifty-eight percent were female, and the mean age of users was 62 years of age. Haloperidol and thioridazine were the most frequently received drugs. Mean annual exposure to antipsychotics was 0.43% of the HMO population; estimated duration of exposure was 170 days; and estimated mean daily dose was 176 mg of chlorpromazine equivalents. Duration of exposure and mean daily dose were directly related. Both were also related to sex and age of users. Antipsychotic users were more likely to be exposed to various therapeutic classes of drugs indicative of chronic diseases. Antipsychotic exposure among ambulatory HMO members appeared to be conservative in terms of prevalence and similar to national experience in terms of daily dose. Estimated days of exposure appeared to place some users at increased risk of developing tardive dyskinesia, and the frequent and varied concomitant drug exposures can complicate treatment
Ambulatory · Antipsychotic · Antipsychotic drug · Chlorpromazine · Concomitant · Drug · Environmental health · Family medicine · Haloperidol · Medical prescription · Pharmacoepidemiology · Population · Psychiatry · Schizophrenia (object-oriented programming) · Tardive dyskinesia · Thioridazine · Emergency Medicine · Health Systems, Economic Evaluations, Quality of Life · Internal Medicine · Medicine · Pharmaceutical Practices and Patient Outcomes · Pharmacology · Pharmacy · Schizophrenia research and treatment
The impact of neuroleptic medication on tardive dyskinesia
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Reducing antipsychotic drug prescribing for nursing home patients
Neuroleptic medication and prescription practices with sheltered-care residents
Prescription Drug Use in 1984 and Changes Over Time
Contact With Health Professionals for the Treatment of Psychiatric and Emotional Problems
Factors Affecting the Utilization of Specialty and General Medical Mental Health Services
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,04 |
| Citation span | 2000 - 2000 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |