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The Mortality Risk Score and the ADG Score

Two Points-Based Scoring Systems for the Johns Hopkins Aggregated Diagnosis Groups to Predict Mortality in a General Adult Population Cohort in Ontario, Canada

Bibliographic Data

ID9103042
AuthorsPeter C Austin (0000-0003-3337-233X, Institute for Clinical Evaluative Sciences, corresponding author), Carl van Walraven (0000-0002-8390-0930, Institute for Clinical Evaluative Sciences)
Year2011
Volume49
Issue10
Pages940-947
Publication date2011-10-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e318229360e
PMID21921849
OpenAlexW2092233526
LanguageEN
Citations received2
References cited8

BACKGROUND: Logistic regression models that incorporated age, sex, and indicator variables for the Johns Hopkins' Aggregated Diagnosis Groups (ADGs) categories have been shown to accurately predict all-cause mortality in adults. OBJECTIVES: To develop 2 different point-scoring systems using the ADGs. The Mortality Risk Score (MRS) collapses age, sex, and the ADGs to a single summary score that predicts the annual risk of all-cause death in adults. The ADG Score derives weights for the individual ADG diagnosis groups. RESEARCH DESIGN: : Retrospective cohort constructed using population-based administrative data. PARTICIPANTS: All 10,498,413 residents of Ontario, Canada, between the age of 20 and 100 years who were alive on their birthday in 2007, participated in this study. Participants were randomly divided into derivation and validation samples. MEASURES: : Death within 1 year. RESULTS: In the derivation cohort, the MRS ranged from -21 to 139 (median value 29, IQR 17 to 44). In the validation group, a logistic regression model with the MRS as the sole predictor significantly predicted the risk of 1-year mortality with a c-statistic of 0.917. A regression model with age, sex, and the ADG Score has similar performance. Both methods accurately predicted the risk of 1-year mortality across the 20 vigintiles of risk. CONCLUSIONS: The MRS combined values for a person's age, sex, and the John Hopkins ADGs to accurately predict 1-year mortality in adults. The ADG Score is a weighted score representing the presence or absence of the 32 ADG diagnosis groups. These scores will facilitate health services researchers conducting risk adjustment using administrative health care databases

Cohort · Cohort study · Disease · Environmental health · Framingham Risk Score · Logistic regression · Population · Regression analysis · Retrospective cohort study · Risk of mortality · Statistic · Statistics · Autopsy Techniques and Outcomes · Chronic Disease Management Strategies · Demography · Internal Medicine · Mathematics · Medicine · Sepsis Diagnosis and Treatment

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Unique citing works2
Citations per year0,2
Citation span2016 - 2020 (5)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2
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