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Clinical Epidemiology of Single Versus Multiple Substance Use Disorders

Polysubstance Use Disorder

Bibliographic Data

ID9104665
AuthorsIsh P Bhalla (0000-0002-9598-2689, Yale University Department of Psychiatry, corresponding author), Elina A Stefanovics (0000-0003-2843-4735, Yale University Department of Psychiatry, corresponding author), Robert Rosenheck (0000-0003-4314-4592, Yale University, corresponding author), Robert A Rosenheck (Yale University Department of Psychiatry)
Year2017
Volume55
IssueSuppl 2
PagesS24-S32
Publication date2017-09-01
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0000000000000731
PMID28806363
OpenAlexW2742469005
LanguageEN
Citations received19
References cited45

OBJECTIVE: While research on substance abuse has largely focused on people who have a single substance use disorder (SUD), many people abuse multiple substances. Studies have yet to examine the distinctive characteristics of patients diagnosed with more than 1 SUD and how those with polysubstance use disorder (PSUD) differ from those with a single SUD. METHODS: National Veterans Health Administration data from fiscal year 2012 were used to compare veterans diagnosed 1 SUD to veterans diagnosed with 2-3, and >3 SUDs on demographic characteristics, psychiatric and medical diagnoses, medical and psychiatric service utilization, and psychotropic medication fills. Comparisons of the 3 groups were based on bivariate and multiple logistic regression analyses. RESULTS: Of the 472,624 veterans with at least 1 diagnosed SUD, 346,329 (73.2%) had 1 disorder, 113,598 (24.0%) had 2-3, and 12,715 (2.7%) had >3 SUDs. Veterans with higher levels of PSUD were more likely to be black and homeless, were more likely to have hepatic disease as well as schizophrenia, bipolar disorder, major depressive disorder, and personality disorders. Higher levels of PSUD were associated with greater use of psychiatric inpatient care, residential and rehabilitative treatment, and with multiple psychotropic medication prescription fills. CONCLUSIONS: Veterans with PSUD have more severe problems along several dimensions and use more numerous and varied services than those with 1 SUD. This distinctive clinical profile warrants research to develop and evaluate methods for treating patients with complex multimorbid disorders that involve interactions between medical morbidity and psychosocial dysfunction

Biology · Clinical epidemiology · MEDLINE · Psychiatry · Substance use · Epidemiology · Forensic Toxicology and Drug Analysis · Internal Medicine · Medicine · Opioid Use Disorder Treatment · Psychology · Substance Abuse Treatment and Outcomes

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Citations per year2.11
Citation span2017 - 2026 (10)
Highly citedNo

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