Evaluation of Specialized Medication Packaging Combined With Medication Therapy Management

Adherence, Outcomes, and Costs Among Medicaid Patients

Bibliographic Data

ID9104923
AuthorsAlan J Zillich (0000-0002-7495-3678, Indiana University – Purdue University Indianapolis, corresponding author), Heather A W Jaynes, Heather A Jaynes (0000-0002-8517-5680, Purdue University West Lafayette), Margie E Snyder (0000-0003-1482-8020, Purdue University West Lafayette), Jeff Harrison (0000-0001-8478-7469, University of Auckland), Karen Suchanek Hudmon (0000-0002-3713-5510, Purdue University West Lafayette), Carl de Moor (0000-0002-6188-0254), Dustin D French (0000-0003-4064-3206, Indiana University – Purdue University Indianapolis, corresponding author)
Year2012
Volume50
Issue6
Pages485-493
Publication date2012-06-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0b013e3182549d48
PMID22498687
PMCIDPMC4126258
OpenAlexW2327312546
LanguageEN
Citations received3
References cited27

BACKGROUND: This study evaluates the effect of a program combing specialized medication packaging and telephonic medication therapy management on medication adherence, health care utilization, and costs among Medicaid patients. RESEARCH DESIGN: A retrospective cohort design compared Medicaid participants who voluntarily enrolled in the program (n = 1007) compared with those who did not (n = 13,614). Main outcome measures were medication adherence at 12 months, hospital admissions and emergency department visits at 6 and 12 months, and total paid claim costs at 6 and 12 months. Multivariate regression models were used to adjust for the effect of age, sex, race, comorbidities, and 12-month preenrollment health care utilization. RESULTS: Measures of medication adherence were significantly improved in the program cohort compared with the usual care cohort. At 6 months, adjusted all-cause hospitalization was marginally less in the program cohort compared with the usual care cohort [odds ratio = 0.73, 95% confidence interval (CI), 0.54-1.0, P = 0.05]. No statistically significant differences were observed between the 2 cohorts for any of the other adjusted utilization endpoints at 6 or 12 months. Adjusted total cost at 6 and 12 months were higher in the program cohort (6-month cost ratio = 1.76, 95% CI,1.65-1.89; 12-month cost ratio = 1.84, 95% CI,1.72-1.97), primarily because of an increase in prescription costs. Emergency department visits and hospitalization costs did not differ between groups. CONCLUSIONS: : The program improved measures of medication adherence, but the effect on health care utilization and nonpharmacy costs at 6 and 12 months was not different from the usual care group. Reasons for these findings may reflect differences in the delivery of the specialized packaging and the medication therapy management program, health care behaviors in this Medicaid cohort, unadjusted confounding, or time required for the benefit of the intervention to manifest

Cohort · Cohort study · Confidence interval · Emergency department · Family medicine · Health care · Medicaid · Medical prescription · Medicare Advantage · Medication therapy management · Odds ratio · Pharmacist · Psychiatry · Retrospective cohort study · Chronic Disease Management Strategies · Emergency Medicine · Internal Medicine · Medication Adherence and Compliance · Medicine · Mobile Health and mHealth Applications · Pharmacy

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