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Construct Validity and Factor Structure of Survey-based Assessment of Cost-related Medication Burden

Bibliographic Data

ID9105051
AuthorsMehmet Burcu (0000-0003-4572-0987, corresponding author), G Caleb Alexander (0000-0002-5622-2986, Johns Hopkins University), Xinyi Ng (0000-0002-0736-8276, corresponding author), Donna Harrington (University of Maryland, Baltimore)
Year2015
Volume53
Issue2
Pages199-206
Publication date2015-02-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueMedical Care (JOURNAL)
Journal identifiersISSN: 0025-7079 • E-ISSN: 1537-1948
PublisherOvid Technologies (Wolters Kluwer Health) (PUBLISHER)
DOI10.1097/mlr.0000000000000286
PMID25517070
OpenAlexW2316734598
LanguageEN
Citations received3
References cited36

BACKGROUND: Millions of Americans are burdened by out-of-pocket prescription costs. Although many survey measures have been developed to assess this burden, the construct validity and the factor structure of these instruments have not been rigorously assessed. OBJECTIVES: To characterize the factor structure and the construct validity of items assessing cost-related medication burden. METHODS: We applied exploratory factor and confirmatory factor analyses to the 2009 Medicare Current Beneficiary Survey, focusing on 10 items assessing cost-related mediation burden among a nationally representative sample of community-dwelling Medicare beneficiaries. The fit of competing models was compared using several indices. RESULTS: The study population (N=8777) was predominantly aged over 65 years (83.3%), female (54.4%), and white (84.3%). Two distinct factors were present for the medication cost-reduction strategies: (1) cost-related medication nonadherence and (2) drug-shopping behaviors, not directly impacting medication compliance. The two factors were moderately correlated (r=0.55), highlighting the presence of a 2 distinct but related constructs for cost-related medication burden. An item assessing the use of mail or internet pharmacies did not load well on either factor and may not necessarily measure medication-related cost burden. An item assessing reduced spending on basic needs loaded strongly on the same factor with the cost-related medication nonadherence items, suggesting they together may represent extreme compensatory behaviors that may adversely affect health outcomes. CONCLUSIONS: Two distinct constructs were derived from these items examining cost-related medication burden. Although cost-related medication burden is often associated with nonadherence, drug-shopping behaviors that do not directly impact adherence are also important measure of this burden

Confirmatory factor analysis · Construct validity · Environmental health · Exploratory factor analysis · Medical prescription · Medicare Part D · Population · Prescription drug · Psychometrics · Structural equation modeling · Clinical Psychology · Economic and Financial Impacts of Cancer · Medication Adherence and Compliance · Medicine · Nursing · Pharmaceutical Practices and Patient Outcomes

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Unique citing works3
Citations per year0,3
Citation span2016 - 2021 (6)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 3

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