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Performance of rubella suspect case definition

Implications for surveillance

Datos Bibliográficos

ID9260427
AutoresSolange Artimos De Oliveira (0000-0002-1862-2348, Hospital Universitário Antônio Pedro), Luiz Antônio Bastos Camacho (0000-0003-4656-1914, Fundação Oswaldo Cruz), Antonio Carlos Pereira (0000-0003-1703-8171, Hospital Universitário Antônio Pedro), Antonio Carlos de Medeiros Pereira (Hospital Universitário Antônio Pedro), Marília Mattos Bulhões (Ministério da Saúde, Brasil), Angélica Fortes Aguas (Fundação Municipal de Saúde de Niterói, Brasil), Marilda Agudo Mendonça Teixeira De Siqueira (0000-0003-4685-9817, Fundação Oswaldo Cruz), Marilda Mendonça Siqueira (Fundação Oswaldo Cruz)
Año2006
Volumen40
Número3
Páginas450-456
Fecha de publicación2006-06-01
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaRevista de Saúde Pública (JOURNAL)
Identificadores de la revistaISSN: 0034-8910 • E-ISSN: 0034-8910
EditorialFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/s0034-89102006000300013
PMID16810369
OpenAlexW1972833048
SCIELO_PIDS0034-89102006000300013
IdiomaEN
Citas recibidas1
Referencias citadas9

OBJECTIVE: To assess the performance of the rubella suspect case definition among patients with rash diseases seen at primary care units. METHODS: From January 1994 to December 2002, patients with acute rash, with or without fever, were seen at two large primary health care units and at a public general hospital in the municipality of Niterói, metropolitan area of Rio de Janeiro, Brazil. Data from clinical and serologic assessment were used to estimate the positive predictive values of the definition of rubella suspect case from the Brazilian Ministry of Health and other combination of signs/symptoms taking serologic status as the reference. Serum samples were tested for anti-rubella virus IgM using commercially available enzyme immunoassays. Positive predictive values and respective 95% confidence intervals were calculated. RESULTS: A total of 1,186 patients with an illness characterized by variable combinations of rash with fever, arthropathy and lymphadenopathy were studied. Patients with rash, regardless of other signs and symptoms, had 8.8% likelihood of being IgM-positive for rubella. The Brazilian suspect case definition (fever and lymphadenopathy in addition to rash) had low predictive value (13.5%). This case definition would correctly identify 42.3% of the IgM-positive cases, and misclassify 26.1% of the IgM-negative cases. CONCLUSIONS: These results support the recommendation to investigate and collect clinical specimens for laboratory diagnosis of all cases of rash, for surveillance purposes. Although this strategy may increase costs, the benefits of interrupting the circulation of rubella virus and preventing the occurrence of congenital rubella syndrome should pay off

Antibody · Measles · Rash · Rubella · Rubella virus · Serology · Vaccination · Immunology · Internal Medicine · Medicine · Parvovirus B19 Infection Studies · Respiratory viral infections research · Virology and Viral Diseases · Pediatrics

  • Trends of rubella incidence during a 5-year period of case based surveillance in Zimbabwe

    Open Access•Simbarashe Chimhuya, Portia Manangazira et al.•BMC Public Health•2015

Obras citantes distintas1
Citas por año0,09
Intervalo de citas2015 - 2015 (1)
Velocidad de citaciónhistorical
Altamente citadoNo
Tipos de citaNeutras: 1
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