Laura Cunha Rodrigues
Biographic Data
| ID | 3667330 |
|---|---|
| NAME | Laura Cunha Rodrigues |
| GIVEN NAMES | Laura Cunha |
| FAMILY NAME | Rodrigues |
| SIGNATURE | RODRIGUES L C |
| AFFILIATIONS | London School of Hygiene & Tropical Medicine |
| ORCID | 0000-0001-9008-660X |
| VERIFIED | Yes |
| TOTAL WORKS | 64 |
| TOTAL CITATIONS | 130 |
| AUTHOR COUNT | 64 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1973 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 6 |
Sociodemographic Factors and Childhood Growth
Children born in later time periods showed better growth trajectories, which may reflect the combined effects of sanitation improvements, economic development, and other societal changes in Brazil during this period. Further research using experimental or quasi-experimental designs is needed to isolate the specific contribution of sanitation to child growth
Characterization of 843 children with Zika-related microcephaly in the first three years of life
One of the main gaps in characterizing the congenital Zika syndrome (CZS) up to now is the small number of participants in individual studies. Pooling the data together overcomes the sample size-related limitations of individual studies and provides an opportunity for investigating heterogeneity between studies and, as appropriate, to better characterize the CZS . This study aims to describe adverse anthropometric, clinical, and neuroimaging outc…
Evaluating the relationship between conditional cash transfer programme on preterm births
An income transfer programme for pregnant women of low-socioeconomic status, conditional to attending prenatal care appointments, has been associated with a reduction in extremely preterm births. These programmes could be essential in achieving Sustainable Development Goals
Socioeconomic risk markers of congenital Zika syndrome
While it is well known that socioeconomic markers are associated with a higher risk of arbovirus infections, research on the relationship between socioeconomic factors and congenital Zika syndrome (CZS) remains limited. This study investigates the relationship between socioeconomic risk markers and live births with CZS in Brazil. We conducted a population-based study using data from all registered live births in Brazil (Live Births Information Sy…
Epidemiological characteristics and temporal trends of new leprosy cases in Brazil
Our study aims to describe trends in new case detection rate (NCDR) of leprosy in Brazil from 2006 to 2017 overall and in subgroups, and to analyze the evolution of clinical and treatment characteristics of patients, with emphasis on cases diagnosed with grade 2 physical disabilities. We conducted a descriptive study to analyze new cases of leprosy registered in the Brazilian Information System for Notificable Diseases (SINAN), from 2006-2017. We…
A new insight into the definition of microcephaly in Zika congenital syndrome era
This study aimed to compare the anthropometric measurements and body proportionalities of neonates born before the Zika virus epidemic with those born during this period. We compared 958 neonates born during the pre-Zika epidemic with 264 neonates born during the epidemic period. The newborns had their head circumference, weight, and length classified according to the Fenton & Kim growth chart. We considered disproportionate those individuals tha…
Spatiotemporal Analysis of the Population Risk of Congenital Microcephaly in Pernambuco State, Brazil
Since an outbreak in Brazil, which started in 2015, Zika has been recognized as an important cause of microcephaly. The highest burden of this outbreak was in northeast Brazil, including the state of Pernambuco. The prevalence of congenital microcephaly in Pernambuco state was estimated from the RESP (Registro de Eventos em Saúde Pública) surveillance system, from August 2015 to August 2016 inclusive. The denominators were estimated at the munici…
Uso de registro informatizado de imunização na vigilância de eventos adversos pós-vacina
OBJETIVO: Descrever os eventos adversos pós-vacina ocorridos em crianças com até dois anos de idade e analisar a tendência desses eventos, entre 2000 e 2013, em Araraquara, SP, Brasil. MÉTODOS: Estudo descritivo com dados da vigilância passiva de eventos adversos pós-vacina, disponíveis no registro informatizado de imunização do prontuário eletrônico do serviço municipal de saúde (Sistema Juarez). As variáveis de estudo foram: idade, sexo, vacina…
Biogeographical ancestry is associated with socioenvironmental conditions and infections in a Latin American urban population
Racial inequalities are observed for different diseases and are mainly caused by differences in socioeconomic status between ethnoracial groups. Genetic factors have also been implicated, and recently, several studies have investigated the association between biogeographical ancestry (BGA) and complex diseases. However, the role of BGA as a proxy for non-genetic health determinants has been little investigated. Similarly, studies comparing the as…
Social, Environmental and Behavioral Determinants of Asthma Symptoms in Brazilian Middle School Students—A National School Health Survey (Pense 2012)
Biological and psychosocial factors are recognized contributors to the worldwide burden of asthma. However, the relationship between psychosocial factors and asthma symptoms among students in low- and middle-income countries remains underexplored. We aimed to identify socioeconomic, environmental, psychosocial, family-related and lifestyle factors associated with the self-reporting of asthma symptoms in Brazilian adolescents. This is a cross-sect…
Microcephaly epidemic related to the Zika virus and living conditions in Recife, Northeast Brazil
This study showed that those residing in areas with precarious living conditions had a higher prevalence of microcephaly compared with populations with better living conditions
Avaliação de coberturas vacinais de crianças em uma cidade de médio porte (Brasil) utilizando registro informatizado de imunização
Dados administrativos mostram altas coberturas vacinais no Brasil, porém não há avaliação da validade e oportunidade de aplicação das doses, nem se o esquema vacinal está completo. Este estudo avaliou as coberturas oportunas e atualizadas de crianças de 12 a 24 meses de idade. Estudo longitudinal de base populacional em Araraquara, São Paulo, uma cidade de médio porte predominantemente urbana, utilizando dados do Sistema Juarez, um registro infor…
Migration to middle-income countries and tuberculosis—global policies for global economies
BACKGROUND: International migration to middle-income countries is increasing and its health consequences, in particular increasing transmission rates of tuberculosis (TB), deserve consideration. Migration and TB are a matter of concern in high-income countries and targeted screening of migrants for active and latent TB infection is a main strategy to manage risk and minimize transmission. In this paper, we discuss some aspects of TB control and m…
ZikaPLAN
The ongoing Zika virus (ZIKV) outbreak in Latin America, the Caribbean, and the Pacific Islands has underlined the need for a coordinated research network across the whole region that can respond rapidly to address the current knowledge gaps in Zika and enhance research preparedness beyond Zika. The European Union under its Horizon 2020 Research and Innovation Programme awarded three research consortia to respond to this need. Here we present the…
Teixeira and Rodrigues Respond
Teixeira and Rodrigues Respond Affiliation Maria G. Teixeira PhD, and Laura C. Rodrigues PhDMaria G. Teixeira is with the Instituto de Saúde Coletiva–Universidade Federal da Bahia, Salvador, Brazil. Laura C. Rodrigues is with the London School of Hygiene and Tropical Medicine, London, England.CopyRightCorrespondence should be sent to Laura C. Rodrigues, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, England (e-mail: l…
Zika
The Epidemic of Zika Virus–Related Microcephaly in Brazil
We describe the epidemic of microcephaly in Brazil, its detection and attempts to control it, the suspected causal link with Zika virus infection during pregnancy, and possible scenarios for the future. In October 2015, in Pernambuco, Brazil, an increase in the number of newborns with microcephaly was reported. Mothers of the affected newborns reported rashes during pregnancy and no exposure to other potentially teratogenic agents. Women deliveri…
Initial Description of the Presumed Congenital Zika Syndrome
Objectives. To provide an initial description of the congenital syndrome presumably associated with infection by Zika virus compared with other syndromes including congenital infections of established etiologies. Methods. We provide an overview of a published case series of 35 cases, a clinical series of 104 cases, and published and unpublished reports of clinical and laboratory findings describing cases diagnosed since the beginning of the epide…
Microcefalia no Estado de Pernambuco, Brasil
O aumento das notificações de casos de microcefalia em Pernambuco, Brasil, e no Nordeste caracterizou uma epidemia que levou o Ministério da Saúde a decretar emergência nacional de saúde pública. Inicialmente, o Ministério da Saúde definiu como suspeitos recém-nascidos de 37 semanas ou mais de idade gestacional (IG) e com perímetro cefálico (PC) ≤ 33cm, tendo, em dezembro de 2015, reduzido essa medida para 32cm. Este estudo objetivou estimar a ac…
Empirical treatment for TB in HIV
Higher mortality in PLHIV reporting a current cough without bacteriological confirmation of tuberculosis was identified for those with a CD4 cell count <200, abnormal chest X-ray, anemia and empirical treatment for tuberculosis. Mortality was not significantly higher in those empirically treated for TB, who had three characteristics suggestive of the disease (abnormal chest X-ray, history of TB treatment, AFB sputum smear or M.tb culture testing)…
Food and nutrition insecurity
Objective To evaluate the association between food and nutrition insecurity and asthma in children from Latin America. Design Cross-sectional study. Setting São Francisco do Conde, Bahia, north-eastern Brazil. Subjects The study included 1307 children aged 6–12 years from public elementary schools. Asthma symptoms were collected using a questionnaire that was translated and adapted from the International Study of Asthma and Allergies in Childhood…
Weight gain in the first two years of life, asthma and atopy
Objective To evaluate the association between weight gain in the first two years of life and the occurrence of wheezing, asthma, serum IgE, skin reactivity and pulmonary function. Design Cohort study. Setting The metropolitan region of Salvador, Bahia, Brazil. Subjects The association was studied between 1997 and 2005 in 669 children up to 11 years of age. Data were collected on asthma and risk factors, both current factors and those present in t…
Padrões alimentares de crianças menores de cinco anos de idade residentes na capital e em municípios da Bahia, Brasil, 1996 e 1999/2000
Estudo transversal com 3.817 pré-escolares, 1.770 residentes em Salvador, Bahia, Brasil, e 2.047 nas áreas urbana e rural de 10 municípios baianos. Utilizou-se recordatório de 24 horas (R24h) e empregou-se análise fatorial por componentes principais com objetivo de identificar e comparar os principais padrões alimentares dessas crianças. Estratificou-se a amostra por idade e área. Antes dos seis meses de vida o leite materno compôs o 2o e 3o padr…
Padrão alimentar, asma e sibilo atópico e não atópico em crianças e adolescentes
Avaliou-se, em estudo transversal, a influência do padrão alimentar sobre a ocorrência de sibilo e asma atópica e não atópica em 1.168 crianças e adolescentes em Salvador, Bahia, Brasil. Sibilo e sintomas de asma nos últimos 12 meses foram obtidos por meio do questionário ISAAC. Atopia foi definida pela presença de IgE específica a aerolérgenos. Questionário de frequência alimentar foi usado para definir padrões alimentares. Empregou-se regressõe…
The second study of infectious intestinal disease (IID2)
Elderly populations have a high propensity for recurrent IID. More detailed studies are needed to identify vulnerable subgroups and susceptibility factors, and inform adequate control policies among the elderly
Initial Description of the Presumed Congenital Zika Syndrome
Objectives. To provide an initial description of the congenital syndrome presumably associated with infection by Zika virus compared with other syndromes including congenital infections of established etiologies. Methods. We provide an overview of a published case series of 35 cases, a clinical series of 104 cases, and published and unpublished reports of clinical and laboratory findings describing cases diagnosed since the beginning of the epide…
Fatores de risco para mortalidade neonatal precoce
OBJETIVO: Avaliar os fatores de risco da mortalidade neonatal precoce. MÉTODOS: Estudo caso-controle de base populacional com 146 óbitos neonatais precoces e amostra de 313 controles obtidos entre os sobreviventes ao período neonatal, na região sul do município de São Paulo, no período de 1/8/2000 a 31/1/2001. As informações foram obtidas por meio de entrevistas domiciliares e prontuários hospitalares. Foi realizada análise hierarquizada em cinco…
The Epidemic of Zika Virus–Related Microcephaly in Brazil
We describe the epidemic of microcephaly in Brazil, its detection and attempts to control it, the suspected causal link with Zika virus infection during pregnancy, and possible scenarios for the future. In October 2015, in Pernambuco, Brazil, an increase in the number of newborns with microcephaly was reported. Mothers of the affected newborns reported rashes during pregnancy and no exposure to other potentially teratogenic agents. Women deliveri…
Validade das informações das declarações de nascidos vivos com base em estudo de caso-controle
A pesquisa Mortalidade Perinatal na Região Sul do Município de São Paulo: Um Estudo Caso-controle de Base Populacional possibilitou a comparação das informações das declarações de nascido vivo (DN) com as obtidas em entrevistas com as mães e o registro nos prontuários hospitalares, e permitiu avaliar diferenças de registro nos nascimentos que resultaram em óbitos neonatais precoces (casos) e sobreviventes (controles). Para avaliar a confiabilidad…
Risk-factors for antepartum fetal deaths in the city of São Paulo, Brazil
OBJECTIVE: To assess risk factors for antepartum fetal deaths. METHODS: A population-based case-control study was carried out in the city of São Paulo from August 2000 to January 2001. Subjects were selected from a birth cohort from a linked birth and death certificate database. Cases were 164 antepartum fetal deaths and controls were drawn from a random sample of 313 births surviving at least 28 days. Information was collected from birth and dea…
Prevalência de parasitos intestinais na comunidade indígena Maxakali, Minas Gerais, Brasil, 2009
O objetivo deste estudo foi determinar a prevalência de parasitos intestinais na etnia Maxakali em Minas Gerais, Brasil. Os exames parasitológico das fezes foram realizados através da técnica TF-Test, sendo as amostras fecais coletadas em três dias alternados, em tubos independentes, contendo formol a 10%, unificados para dupla filtragem por centrifugação. Triplicatas de uma alíquota do sedimento foram examinadas em microscópio (10x e 40x) para i…
Microcefalia no Estado de Pernambuco, Brasil
O aumento das notificações de casos de microcefalia em Pernambuco, Brasil, e no Nordeste caracterizou uma epidemia que levou o Ministério da Saúde a decretar emergência nacional de saúde pública. Inicialmente, o Ministério da Saúde definiu como suspeitos recém-nascidos de 37 semanas ou mais de idade gestacional (IG) e com perímetro cefálico (PC) ≤ 33cm, tendo, em dezembro de 2015, reduzido essa medida para 32cm. Este estudo objetivou estimar a ac…
Characteristics and circumstances of falls leading to severe fractures in elderly people in Rio de Janeiro, Brazil
The circumstances associated with falls among elderly people have been well described in some developed countries, but little is known about such accidents in middle-income countries. The aim of this paper is to report the circumstances and characteristics associated with falls leading to severe fractures among elderly people living in Rio de Janeiro, Brazil. Cases were obtained from two case-control studies on risk factors for severe fractures d…
Partos domiciliares acidentais na região sul do Município de São Paulo
OBJETIVO: Identificar a freqüência, o risco de mortalidade fetal e neonatal precoce e os determinantes do parto domiciliar acidental. MÉTODOS: Estudo caso-controle de base populacional sobre mortes fetais e neonatais precoces realizado na região sul do Município de São Paulo. Foram coletados dados em entrevistas domiciliares e de prontuários hospitalares. Os motivos referidos pelas mães para a ocorrência de partos domiciliares foram obtidos nas e…
Tuberculose em Salvador
OBJETIVO: A tuberculose é uma das maiores causas de mortalidade no mundo, porém seus efeitos econômicos são pouco conhecidos. O objetivo do estudo foi o de estimar os custos do tratamento e prevenção da tuberculose para o sistema de saúde (público e privado) e para as famílias. MÉTODOS: O estudo foi realizado no município de Salvador, BA, em 1999. Os dados para estimação dos custos para o sistema de saúde foram coletados nas secretarias de saúde,…
Padrões alimentares de crianças menores de cinco anos de idade residentes na capital e em municípios da Bahia, Brasil, 1996 e 1999/2000
Estudo transversal com 3.817 pré-escolares, 1.770 residentes em Salvador, Bahia, Brasil, e 2.047 nas áreas urbana e rural de 10 municípios baianos. Utilizou-se recordatório de 24 horas (R24h) e empregou-se análise fatorial por componentes principais com objetivo de identificar e comparar os principais padrões alimentares dessas crianças. Estratificou-se a amostra por idade e área. Antes dos seis meses de vida o leite materno compôs o 2o e 3o padr…
Sobrevida e fatores de risco para mortalidade neonatal em uma coorte de nascidos vivos de muito baixo peso ao nascer, na Região Sul do Município de São Paulo, Brasil
Estudos populacionais sobre mortalidade neonatal de nascimentos de muito baixo peso ao nascer contribuem para identificar sua complexa rede de fatores de risco. Foi estudada uma coorte de 213 recém-nascidos com peso inferior a 1.500g (112 óbitos neonatais e 101 sobreviventes) na Região Sul do Município de São Paulo, Brasil, em 2000/2001. Foram realizadas entrevistas domiciliares e obtidos dados de prontuários hospitalares. Foi realizada análise d…
Perfil de pacientes que evoluem para óbito por tuberculose no município de São Paulo, 2002
OBJETIVO: Descrever o perfil de pacientes adultos residentes no município de São Paulo que evoluíram para óbito associado à tuberculose, segundo fatores biológicos, ambientais e institucionais. MÉTODOS: Estudo descritivo, abrangendo todos os óbitos por tuberculose (N=416) ocorridos em 2002, entre maiores de 15 anos. Os dados analisados foram obtidos do Sistema Municipal de Informações de Mortalidade, prontuários hospitalares, Serviço de Verificaç…
Factors associated with treatment failure, dropout, and death in a cohort of tuberculosis patients in Recife, Pernambuco State, Brazil
A cohort of cases initiating tuberculosis treatment from May 2001 to July 2003 was followed in Recife, Pernambuco State, Brazil, to investigate biological, clinical, social, lifestyle, and healthcare access factors associated with three negative tuberculosis treatment outcomes (treatment failure, dropout, and death) separately and as a group. Treatment failure was associated with treatment delay, illiteracy, and alcohol consumption. Factors assoc…
The Validity of Verbal Autopsies for Assessing the Causes of Institutional Maternal Death
This report presents data from a study carried out in three African countries to assess the validity of verbal autopsies--based on information about symptoms and signs observed antemortem by relatives or associates of deceased individuals--for determining the causes of institutional maternal death. The validity of the verbal autopsy was assessed for each cause of death; and for groups of "direct" and "indirect" maternal causes, by comparing the v…
The Small Area Health Statistics Unit
STUDY OBJECTIVE--The Small Area Health Statistics Unit (SAHSU) was established at the London School of Hygiene and Tropical Medicine in response to a recommendation of the enquiry into the increased incidence of childhood leukaemia near Sellafield, the nuclear reprocessing plant in West Cumbria. The aim of this paper was to describe the Unit's methods for the investigation of health around point sources of environmental pollution in the United Ki…
Factors influencing childhood immunisation in an urban area of Brazil
STUDY OBJECTIVE--The aim was to examine the factors associated with incomplete vaccination in an urban area in Sao Paulo, Brazil; and to explore whether differences in vaccine coverage in the catchment area of health centres remain after the demographic constitution of the population in these areas is controlled for. DESIGN--The children were selected as controls for a case-control study. 455 children were selected at random (but age matched) fro…
The Spanish Riots of 1766
Journal Article THE SPANISH RIOTS OF 1766 Get access Laura Rodrigues Laura Rodrigues St. Hugh's CollegeOxford Search for other works by this author on: Oxford Academic Google Scholar Past & Present, Volume 59, Issue 1, May 1973, Pages 117–146, https://doi.org/10.1093/past/59.1.117 Published: 01 May 1973
Zika
Maternal mental health and social support
BACKGROUND: Atopic and non-atopic asthma have distinct risk factors and immunological mechanisms, and few studies differentiate between the impacts of psychosocial factors on the prevalence of these disease phenotypes. The authors aimed to identify whether the effect of maternal mental health on prevalence of asthma symptoms differs between atopic and non-atopic children, taking into account family social support. METHODS: This is a cross-section…
Epidemiological characteristics and temporal trends of new leprosy cases in Brazil
Our study aims to describe trends in new case detection rate (NCDR) of leprosy in Brazil from 2006 to 2017 overall and in subgroups, and to analyze the evolution of clinical and treatment characteristics of patients, with emphasis on cases diagnosed with grade 2 physical disabilities. We conducted a descriptive study to analyze new cases of leprosy registered in the Brazilian Information System for Notificable Diseases (SINAN), from 2006-2017. We…
Resposta brasileira à tuberculose
Tuberculosis (TB) has affected mankind for more than 8,000 years. Before the mid-19th century TB was not recognized as a contagious disease and was attributable to several causes such as hereditary, miasmas, and other environmental and social determinants. But, in 1882, Robert Koch identifi ed Mycobacterium tuberculosis, which allowed to defi ning TB as an infectious disease. Then blossoming biomedical research started its quest for vaccines and …
Sensibilidade e especificidade da leitura da cicatriz vacinal do BCG
OBJETIVO: Validar a utilização da cicatriz vacinal de BCG como um indicador de vacinação. MÉTODOS: Foi realizado um estudo transversal em 52.348 escolares, entre 6 e 14 anos de idade, que possuíam exame de cicatriz vacinal do BCG e que participaram de um ensaio clínico randomizado e controlado na cidade de Manaus, Brasil. Os dados da leitura da cicatriz vacinal foram comparados com a informação sobre a vacinação passada fornecida pelos cartões va…
The Spanish Riots of 1766
Journal Article THE SPANISH RIOTS OF 1766 Get access Laura Rodrigues Laura Rodrigues St. Hugh's CollegeOxford Search for other works by this author on: Oxford Academic Google Scholar Past & Present, Volume 59, Issue 1, May 1973, Pages 117–146, https://doi.org/10.1093/past/59.1.117 Published: 01 May 1973
BCG vaccination in the first year of life protects children of Indian subcontinent ethnic origin against tuberculosis in England
STUDY OBJECTIVE--The aim was to assess the protection conferred by BCG given during the first year of life against tuberculosis among children of Asian ethnic origin born in England. DESIGN--This was a matched case-control study. SETTING--Cases were selected from notifications of tuberculosis and controls were selected from child health or school health records in 14 English health districts. PARTICIPANTS--111 cases of childhood tuberculosis with…
The Small Area Health Statistics Unit
STUDY OBJECTIVE--The Small Area Health Statistics Unit (SAHSU) was established at the London School of Hygiene and Tropical Medicine in response to a recommendation of the enquiry into the increased incidence of childhood leukaemia near Sellafield, the nuclear reprocessing plant in West Cumbria. The aim of this paper was to describe the Unit's methods for the investigation of health around point sources of environmental pollution in the United Ki…
Factors influencing childhood immunisation in an urban area of Brazil
STUDY OBJECTIVE--The aim was to examine the factors associated with incomplete vaccination in an urban area in Sao Paulo, Brazil; and to explore whether differences in vaccine coverage in the catchment area of health centres remain after the demographic constitution of the population in these areas is controlled for. DESIGN--The children were selected as controls for a case-control study. 455 children were selected at random (but age matched) fro…
Sudden infant death syndrome
STUDY OBJECTIVE--The aim was to investigate whether the winter increase in risk of sudden infant death was similar across social classes. DESIGN--This was an unmatched case-control study using routine data. SETTING--Cases and controls were selected from files holding routine birth and death certificate data for England and Wales for 1986. SUBJECTS--Cases were deaths in the first year of life occurring in the summer or the winter of 1986 with ment…
The Validity of Verbal Autopsies for Assessing the Causes of Institutional Maternal Death
This report presents data from a study carried out in three African countries to assess the validity of verbal autopsies--based on information about symptoms and signs observed antemortem by relatives or associates of deceased individuals--for determining the causes of institutional maternal death. The validity of the verbal autopsy was assessed for each cause of death; and for groups of "direct" and "indirect" maternal causes, by comparing the v…
A case-control study of autism and mumps-measles-rubella vaccination using the general practice research database
Electronic health databases offer tremendous opportunities for evaluating the adverse effects of vaccines. However there is much scope for bias and confounding. The rigorous validation of all diagnoses and the collection of additional information by parental questionnaire in this study are essential to minimise the possibility of misleading results
Factors associated with HIV infection are not the same for all women
Study objectives: To determine if factors associated with HIV infection vary between subpopulations of women resident in Great Britain. Design: Case-control analyses on already existing datasets. Setting: Great Britain. Participants: 317 cases selected from a MRC Collaborative Study of HIV Infection in Women and 3635 controls selected from a National Survey of Sexual Attitudes and Lifestyles. Main results: Factors associated with HIV infection va…
Tuberculin reactivity in a population of schoolchildren with high BCG vaccination coverage
In Brazilian schoolchildren, BCG-induced tuberculin reactivity is indistinguishable, for results under 15 mm, from reactivity induced by Mycobacterium tuberculosis infection. BCG revaccination at school age increases the degree of BCG-induced tuberculin reactivity found among schoolchildren. This information should be taken into account in tuberculin skin test surveys intended to estimate M. tuberculosis prevalence or to assess transmission patte…
Sensibilidade e especificidade da leitura da cicatriz vacinal do BCG
OBJETIVO: Validar a utilização da cicatriz vacinal de BCG como um indicador de vacinação. MÉTODOS: Foi realizado um estudo transversal em 52.348 escolares, entre 6 e 14 anos de idade, que possuíam exame de cicatriz vacinal do BCG e que participaram de um ensaio clínico randomizado e controlado na cidade de Manaus, Brasil. Os dados da leitura da cicatriz vacinal foram comparados com a informação sobre a vacinação passada fornecida pelos cartões va…
Validation of the diagnosis of autism in general practitioner records
This study provides evidence that the positive predictive value of a diagnosis of autism recorded in the GPRD is high
Current strategy for leprosy control in Brazil
La estrategia actual para el control de la lepra en Brasil se basa en dos actividades principales: la detección precoz de casos y el tratamiento de casos con farmacoterapia combinada. Además de dichas medidas, se realizan esfuerzos complementarios para identificar los contactos domésticos para el diagnóstico precoz y la vacunación con el bacilo de Calmette-Guérin (BCG). Sin embargo, la eficacia de estas acciones a la hora de reducir la incidencia…
Risk factors for treatment delay in pulmonary tuberculosis in Recife, Brazil
In this urban area, delays seem to be related to unemployment and general attitudes towards health. Although they reflect the way health services are organized, delays are not associated with access to care
Partos domiciliares acidentais na região sul do Município de São Paulo
OBJETIVO: Identificar a freqüência, o risco de mortalidade fetal e neonatal precoce e os determinantes do parto domiciliar acidental. MÉTODOS: Estudo caso-controle de base populacional sobre mortes fetais e neonatais precoces realizado na região sul do Município de São Paulo. Foram coletados dados em entrevistas domiciliares e de prontuários hospitalares. Os motivos referidos pelas mães para a ocorrência de partos domiciliares foram obtidos nas e…
Tuberculose em Salvador
OBJETIVO: A tuberculose é uma das maiores causas de mortalidade no mundo, porém seus efeitos econômicos são pouco conhecidos. O objetivo do estudo foi o de estimar os custos do tratamento e prevenção da tuberculose para o sistema de saúde (público e privado) e para as famílias. MÉTODOS: O estudo foi realizado no município de Salvador, BA, em 1999. Os dados para estimação dos custos para o sistema de saúde foram coletados nas secretarias de saúde,…
Validade das informações das declarações de nascidos vivos com base em estudo de caso-controle
A pesquisa Mortalidade Perinatal na Região Sul do Município de São Paulo: Um Estudo Caso-controle de Base Populacional possibilitou a comparação das informações das declarações de nascido vivo (DN) com as obtidas em entrevistas com as mães e o registro nos prontuários hospitalares, e permitiu avaliar diferenças de registro nos nascimentos que resultaram em óbitos neonatais precoces (casos) e sobreviventes (controles). Para avaliar a confiabilidad…
Cost-effectiveness analysis of a state funded programme for control of severe asthma
A programme for control of severe asthma in a developing country can reduce morbidity, improve quality of life and save resources from the health system and patients families
Ecological study of socio-economic indicators and prevalence of asthma in schoolchildren in urban Brazil
The prevalence of asthma in urban areas of Brazil, a middle income country, appears to be higher in cities with more marked poverty or inequality
The importance of research on the association between socioeconomic conditions and asthma
Fatores de risco para mortalidade neonatal precoce
OBJETIVO: Avaliar os fatores de risco da mortalidade neonatal precoce. MÉTODOS: Estudo caso-controle de base populacional com 146 óbitos neonatais precoces e amostra de 313 controles obtidos entre os sobreviventes ao período neonatal, na região sul do município de São Paulo, no período de 1/8/2000 a 31/1/2001. As informações foram obtidas por meio de entrevistas domiciliares e prontuários hospitalares. Foi realizada análise hierarquizada em cinco…
Risk-factors for antepartum fetal deaths in the city of São Paulo, Brazil
OBJECTIVE: To assess risk factors for antepartum fetal deaths. METHODS: A population-based case-control study was carried out in the city of São Paulo from August 2000 to January 2001. Subjects were selected from a birth cohort from a linked birth and death certificate database. Cases were 164 antepartum fetal deaths and controls were drawn from a random sample of 313 births surviving at least 28 days. Information was collected from birth and dea…
Resposta brasileira à tuberculose
Tuberculosis (TB) has affected mankind for more than 8,000 years. Before the mid-19th century TB was not recognized as a contagious disease and was attributable to several causes such as hereditary, miasmas, and other environmental and social determinants. But, in 1882, Robert Koch identifi ed Mycobacterium tuberculosis, which allowed to defi ning TB as an infectious disease. Then blossoming biomedical research started its quest for vaccines and …
Factors associated with treatment failure, dropout, and death in a cohort of tuberculosis patients in Recife, Pernambuco State, Brazil
A cohort of cases initiating tuberculosis treatment from May 2001 to July 2003 was followed in Recife, Pernambuco State, Brazil, to investigate biological, clinical, social, lifestyle, and healthcare access factors associated with three negative tuberculosis treatment outcomes (treatment failure, dropout, and death) separately and as a group. Treatment failure was associated with treatment delay, illiteracy, and alcohol consumption. Factors assoc…
Determinants of cognitive function in childhood
Children's cognitive development in urban contexts in developing countries could be substantially increased by interventions promoting early psychosocial stimulation and preschool experience, together with efforts to prevent low birth weight and promote adequate nutritional status
Perfil de pacientes que evoluem para óbito por tuberculose no município de São Paulo, 2002
OBJETIVO: Descrever o perfil de pacientes adultos residentes no município de São Paulo que evoluíram para óbito associado à tuberculose, segundo fatores biológicos, ambientais e institucionais. MÉTODOS: Estudo descritivo, abrangendo todos os óbitos por tuberculose (N=416) ocorridos em 2002, entre maiores de 15 anos. Os dados analisados foram obtidos do Sistema Municipal de Informações de Mortalidade, prontuários hospitalares, Serviço de Verificaç…
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