Initial Description of the Presumed Congenital Zika Syndrome
Bibliographic Data
Objectives. To provide an initial description of the congenital syndrome presumably associated with infection by Zika virus compared with other syndromes including congenital infections of established etiologies. Methods. We provide an overview of a published case series of 35 cases, a clinical series of 104 cases, and published and unpublished reports of clinical and laboratory findings describing cases diagnosed since the beginning of the epidemic of microcephaly in Brazil. Results. About 60% to 70% of mothers report rash during pregnancy; mainly in the first trimester. Principal features are microcephaly, facial disproportionality, cutis girata, hypertonia/spasticity, hyperreflexia, and irritability; abnormal neuroimages include calcifications, ventriculomegaly, and lissencephaly. Hearing and visual abnormalities may be present. Conclusions. Preliminary data suggest that severe congenital abnormalities are linked to Zika virus infection. Cases have severe abnormalities, and although sharing many characteristics with congenital abnormalities associated with other viral infections, abnormalities presumably linked to the Zika virus may have distinguishing characteristics. These severe neurologic abnormalities may result in marked mental retardation and motor disabilities for many surviving offspring. Policy Implications. Affected nations need to prepare to provide complex and costly multidisciplinary care that children diagnosed with this new congenital syndrome will require
Etiology · Fetus · Hyperreflexia · Lissencephaly · Microcephaly · Pathology · Pregnancy · Ventriculomegaly · Virus · Zika virus · Immunology · Infectious Encephalopathies and Encephalitis · Medicine · Mosquito-borne diseases and control · Surgery · Virology and Viral Diseases · Pediatrics
O cuidado de mães, pais e profissionais oferecidos aos bebês com síndrome congênita do Zika
Spatiotemporal Analysis of the Population Risk of Congenital Microcephaly in Pernambuco State, Brazil
Uma antropologia da transmissão
Economia Política do Zika
Uncertainty in times of medical emergency
Using Supervised Learning Methods to Develop a List of Prescription Medications of Greatest Concern during Pregnancy
The economic burden of congenital Zika Syndrome in Brazil
Epidemic preparedness
Neighbourhood-level income and Zika virus infection during pregnancy in Recife, Pernambuco, Brazil
The legacy of ZikaPLAN
ZikaPLAN
Becoming Without
A Linguagem E a Dimensão Do Corpo Na Síndrome Congênita Do Zika Vírus
Congenital zika syndrome and family impacts
Síndrome congênita do zika e impactos para as famílias
Conhecimento e atitude das gestantes de alto risco sobre a transmissibilidade do vírus zika
Análise do conceito síndrome congênita pelo Zika vírus
Hope and trust in times of Zika
Zika’s Long Haul
Preventing Zika Virus Infections in Pregnant Women
Engaging Human Rights in the Response to the Evolving Zika Virus Epidemic
Síndrome da infecção congênita pelo vírus Zika
Vírus Zika e mulheres
Experiências de pais de crianças nascidas com microcefalia, no contexto da epidemia de Zika, a partir da comunicação do diagnóstico
Epidemia de microcefalia e vírus Zika
A new insight into the definition of microcephaly in Zika congenital syndrome era
Avaliação da implantação da resposta à emergência de saúde pública de microcefalia no Estado de Pernambuco, Brasil
Congenital Zika virus syndrome
Devir-Sem
Analysing the intersection between health emergencies and abortion during Zika in Brazil, El Salvador and Colombia
Women's Reproductive Intentions and Behaviors during the Zika Epidemic in Brazil
| Unique citing works | 31 |
|---|---|
| Citations per year | 3,1 |
| Citation span | 2016 - 2024 (9) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 26 |