J John Mann
Dados Biográficos
| ID | 608115 |
|---|---|
| NOME | J John Mann |
| PRENOMES | J John |
| SOBRENOME | Mann |
| ASSINATURA | MANN J J |
| AFILIAÇÕES | New York Psychoanalytic Society and Institute |
| ORCID | 0000-0002-0265-6586 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 20 |
| TOTAL DE CITAÇÕES | 1 |
| TOTAL COMO AUTOR | 20 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1994 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 1 |
Suicidal behaviour is pathological
Some have challenged the validity of labelling suicidal thoughts and behaviours (STB) as pathological. In this paper, we argue that STB is indeed pathological, thereby, situating suicide prevention within the realm of medicine, complicating calls for the legalisation of medical assistance in dying for individuals whose sole condition is psychiatric (psychiatric medical assistance in dying (MAID)). Evidence shows STB predicts the risk of suicide; …
Social connectedness as a determinant of mental health
Public health and epidemiologic research have established that social connectedness promotes overall health. Yet there have been no recent reviews of findings from research examining social connectedness as a determinant of mental health. The goal of this review was to evaluate recent longitudinal research probing the effects of social connectedness on depression and anxiety symptoms and diagnoses in the general population. A scoping review was p…
Improving Suicide Prevention Through Evidence-Based Strategies
Computerized-Adaptive vs. Traditional Ratings of Depression and Suicidal Thoughts
There is a public health need for improved suicide risk assessment tools. This pilot methodology study compared the assay sensitivity of computerized adaptive tests (CAT) of depression and suicidal ideation vs. traditional ratings in a randomized trial subgroup. The last 20 persons to enroll in a published ketamine trial in suicidal depression were studied. This subgroup received traditional and CAT ratings at baseline, 24 h post-infusion and fol…
Relationship of Brain Glutamate Response to D-Cycloserine and Lurasidone to Antidepressant Response in Bipolar Depression
N-methyl-D-aspartate glutamate-receptor (NMDAR) antagonists such as ketamine have demonstrated efficacy in both major depressive disorder (MDD) and bipolar disorder depression (BP-D). We have previously reported that reduction in Glx (glutamate + glutamine) in the ventromedial prefrontal cortex/anterior cingulate cortex (vmPFC/ACC), measured by proton magnetic resonance spectroscopy ( 1 H MRS) at 3T during a ketamine infusion, mediates the relati…
The Role of Past Suicidal Behavior on Current Suicidality
Past suicide attempts are a significant risk factor for future suicidality. Therefore, the present military-based study examined the past suicidal behavior of soldiers who recently made a severe suicide attempt. Our sample consisted of 65 active-duty soldiers (61.5% males), between the ages of 18 and 28 years old (M = 20.4, SD ± 1.3). The inclusion criterion was a recent severe suicide attempt, requiring at least a 24 h hospitalization. This samp…
Sociodemographic Characteristics, Financial Worries and Serious Psychological Distress in U.S. Adults
Systematic Review of Gut Microbiota and Major Depression
Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have examined the gut microbiome in healthy and affected individuals. We systematically reviewed existing studies comparing gut microbial c…
Depression
Transgenerational Effects of Variable Foraging Demand Stress in Female Bonnet Macaques
Stress coping is an important part of mammalian life, influencing somatic and mental health, social integration, and reproductive success. The experience of early psychological stress helps shape lifelong stress coping strategies. Recent studies have shown that the effects of early stress may not be restricted to the affected generation, but may also be transmitted to offspring. Understanding whether early stress influences development in subsequ…
Prediction of Selective Serotonin Reuptake Inhibitor Response Using Diffusion-Weighted MRI
Pre-treatment differences in serotonergic binding between those who remit to antidepressant treatment and those who do not have been found using Positron Emission Tomography (PET). To investigate these differences, an exploratory study was performed using a second imaging modality, diffusion-weighted MRI (DW-MRI). Eighteen antidepressant-free subjects with Major Depressive Disorder received a 25-direction DW-MRI scan prior to 8 weeks of selective…
The Columbia–Suicide Severity Rating Scale
OBJECTIVE: Research on suicide prevention and interventions requires a standard method for assessing both suicidal ideation and behavior to identify those at risk and to track treatment response. The Columbia-Suicide Severity Rating Scale (C-SSRS) was designed to quantify the severity of suicidal ideation and behavior. The authors examined the psychometric properties of the scale. METHOD: The C-SSRS's validity relative to other measures of suicid…
Suicide Prevention Strategies
CONTEXT: In 2002, an estimated 877,000 lives were lost worldwide through suicide. Some developed nations have implemented national suicide prevention plans. Although these plans generally propose multiple interventions, their effectiveness is rarely evaluated. OBJECTIVES: To examine evidence for the effectiveness of specific suicide-preventive interventions and to make recommendations for future prevention programs and research. DATA SOURCES AND …
Religious Affiliation and Suicide Attempt
OBJECTIVE: Few studies have investigated the association between religion and suicide either in terms of Durkheim's social integration hypothesis or the hypothesis of the regulative benefits of religion. The relationship between religion and suicide attempts has received even less attention. METHOD: Depressed inpatients (N=371) who reported belonging to one specific religion or described themselves as having no religious affiliation were compared…
Adolescent impulsivity predicts adult dominance attainment in male vervet monkeys
Adolescence is characterized by behavioral and physiological changes that prepare individuals for the transition to adulthood. The purpose of this study was to evaluate the effects of behavioral, morphological, neurobiological, and developmental characteristics of adolescent male vervets in predicting later dominance attainment. Thirty‐six adolescent male vervets were tested for social impulsivity by means of the Intruder Challenge test while the…
Suicide in College Students
Despite substantial attention to the problem of suicide among college students over the past several decades, reports on the extent of the problem have been largely inconclusive. This article reviews the findings of major studies of college suicide, noting how variations in campus and student characteristics, as well as inconsistencies in the way student suicides are defined and measured, have limited comparison of conclusions. Current evidence i…
Spanish Adaptation of the Reasonsfor Living Inventory
The Reasons for Living Inventory (RFL) is an instrument to mea sure a range of beliefs potentially important as reasons for not com mitting suicide. There is no Spanish version of this instrument. The adaptation process includes translation, back-translation, review of both versions, and application of the resulting instrument to a bilingual sample from the tar get population. This process allows for assessment of the equivalence between the Engl…
Toward a Clinical Model of Suicidal Behavior in Psychiatric Patients
OBJECTIVE: Risk factors for suicide attempts have rarely been studied comprehensively in more than one psychiatric disorder, preventing estimation of the relative importance and the generalizability of different putative risk factors across psychiatric diagnoses. The authors conducted a study of suicide attempts in patients with mood disorders, psychoses, and other diagnoses. Their goal was to determine the generalizability and relative importanc…
Delayed dispersal and elevated monoaminergic activity in free‐ranging rhesus monkeys
Male rhesus monkeys typically disperse from their groups of birth when they are between 3 and 5 years of age. Some males, however, delay dispersal from their natal groups until after they are 5 years old. The current study evaluated central monoaminergic neurotransmitter activity as a potential correlate of such “delayed” dispersal among 54 randomly selected adolescent and adult male rhesus monkeys ( Macaca mulatta ) captured on Cayo Santiago dur…
Demonstration of an association among dietary cholesterol, central serotonergic activity, and social behavior in monkeys
Epidemiologic studies link plasma cholesterol reduction to increased mortality rates as a result of suicide, violence, and accidents. Deficient central serotonergic activity is similarly associated with violence and suicidal behavior. We investigated the relationship among dietary and plasma cholesterol, social behavior, and the serotonin system as a possible explanation for these findings. Juvenile cynomolgus monkeys (eight female and nine male)…
Suicide in College Students
Despite substantial attention to the problem of suicide among college students over the past several decades, reports on the extent of the problem have been largely inconclusive. This article reviews the findings of major studies of college suicide, noting how variations in campus and student characteristics, as well as inconsistencies in the way student suicides are defined and measured, have limited comparison of conclusions. Current evidence i…
Demonstration of an association among dietary cholesterol, central serotonergic activity, and social behavior in monkeys
Epidemiologic studies link plasma cholesterol reduction to increased mortality rates as a result of suicide, violence, and accidents. Deficient central serotonergic activity is similarly associated with violence and suicidal behavior. We investigated the relationship among dietary and plasma cholesterol, social behavior, and the serotonin system as a possible explanation for these findings. Juvenile cynomolgus monkeys (eight female and nine male)…
Delayed dispersal and elevated monoaminergic activity in free‐ranging rhesus monkeys
Male rhesus monkeys typically disperse from their groups of birth when they are between 3 and 5 years of age. Some males, however, delay dispersal from their natal groups until after they are 5 years old. The current study evaluated central monoaminergic neurotransmitter activity as a potential correlate of such “delayed” dispersal among 54 randomly selected adolescent and adult male rhesus monkeys ( Macaca mulatta ) captured on Cayo Santiago dur…
Toward a Clinical Model of Suicidal Behavior in Psychiatric Patients
OBJECTIVE: Risk factors for suicide attempts have rarely been studied comprehensively in more than one psychiatric disorder, preventing estimation of the relative importance and the generalizability of different putative risk factors across psychiatric diagnoses. The authors conducted a study of suicide attempts in patients with mood disorders, psychoses, and other diagnoses. Their goal was to determine the generalizability and relative importanc…
Spanish Adaptation of the Reasonsfor Living Inventory
The Reasons for Living Inventory (RFL) is an instrument to mea sure a range of beliefs potentially important as reasons for not com mitting suicide. There is no Spanish version of this instrument. The adaptation process includes translation, back-translation, review of both versions, and application of the resulting instrument to a bilingual sample from the tar get population. This process allows for assessment of the equivalence between the Engl…
Suicide in College Students
Despite substantial attention to the problem of suicide among college students over the past several decades, reports on the extent of the problem have been largely inconclusive. This article reviews the findings of major studies of college suicide, noting how variations in campus and student characteristics, as well as inconsistencies in the way student suicides are defined and measured, have limited comparison of conclusions. Current evidence i…
Religious Affiliation and Suicide Attempt
OBJECTIVE: Few studies have investigated the association between religion and suicide either in terms of Durkheim's social integration hypothesis or the hypothesis of the regulative benefits of religion. The relationship between religion and suicide attempts has received even less attention. METHOD: Depressed inpatients (N=371) who reported belonging to one specific religion or described themselves as having no religious affiliation were compared…
Adolescent impulsivity predicts adult dominance attainment in male vervet monkeys
Adolescence is characterized by behavioral and physiological changes that prepare individuals for the transition to adulthood. The purpose of this study was to evaluate the effects of behavioral, morphological, neurobiological, and developmental characteristics of adolescent male vervets in predicting later dominance attainment. Thirty‐six adolescent male vervets were tested for social impulsivity by means of the Intruder Challenge test while the…
Suicide Prevention Strategies
CONTEXT: In 2002, an estimated 877,000 lives were lost worldwide through suicide. Some developed nations have implemented national suicide prevention plans. Although these plans generally propose multiple interventions, their effectiveness is rarely evaluated. OBJECTIVES: To examine evidence for the effectiveness of specific suicide-preventive interventions and to make recommendations for future prevention programs and research. DATA SOURCES AND …
The Columbia–Suicide Severity Rating Scale
OBJECTIVE: Research on suicide prevention and interventions requires a standard method for assessing both suicidal ideation and behavior to identify those at risk and to track treatment response. The Columbia-Suicide Severity Rating Scale (C-SSRS) was designed to quantify the severity of suicidal ideation and behavior. The authors examined the psychometric properties of the scale. METHOD: The C-SSRS's validity relative to other measures of suicid…
Transgenerational Effects of Variable Foraging Demand Stress in Female Bonnet Macaques
Stress coping is an important part of mammalian life, influencing somatic and mental health, social integration, and reproductive success. The experience of early psychological stress helps shape lifelong stress coping strategies. Recent studies have shown that the effects of early stress may not be restricted to the affected generation, but may also be transmitted to offspring. Understanding whether early stress influences development in subsequ…
Prediction of Selective Serotonin Reuptake Inhibitor Response Using Diffusion-Weighted MRI
Pre-treatment differences in serotonergic binding between those who remit to antidepressant treatment and those who do not have been found using Positron Emission Tomography (PET). To investigate these differences, an exploratory study was performed using a second imaging modality, diffusion-weighted MRI (DW-MRI). Eighteen antidepressant-free subjects with Major Depressive Disorder received a 25-direction DW-MRI scan prior to 8 weeks of selective…
Depression
Systematic Review of Gut Microbiota and Major Depression
Background: Recently discovered relationships between the gastrointestinal microbiome and the brain have implications for psychiatric disorders, including major depressive disorder (MDD). Bacterial transplantation from MDD patients to rodents produces depression-like behaviors. In humans, case-control studies have examined the gut microbiome in healthy and affected individuals. We systematically reviewed existing studies comparing gut microbial c…
Sociodemographic Characteristics, Financial Worries and Serious Psychological Distress in U.S. Adults
Improving Suicide Prevention Through Evidence-Based Strategies
Computerized-Adaptive vs. Traditional Ratings of Depression and Suicidal Thoughts
There is a public health need for improved suicide risk assessment tools. This pilot methodology study compared the assay sensitivity of computerized adaptive tests (CAT) of depression and suicidal ideation vs. traditional ratings in a randomized trial subgroup. The last 20 persons to enroll in a published ketamine trial in suicidal depression were studied. This subgroup received traditional and CAT ratings at baseline, 24 h post-infusion and fol…
Relationship of Brain Glutamate Response to D-Cycloserine and Lurasidone to Antidepressant Response in Bipolar Depression
N-methyl-D-aspartate glutamate-receptor (NMDAR) antagonists such as ketamine have demonstrated efficacy in both major depressive disorder (MDD) and bipolar disorder depression (BP-D). We have previously reported that reduction in Glx (glutamate + glutamine) in the ventromedial prefrontal cortex/anterior cingulate cortex (vmPFC/ACC), measured by proton magnetic resonance spectroscopy ( 1 H MRS) at 3T during a ketamine infusion, mediates the relati…
The Role of Past Suicidal Behavior on Current Suicidality
Past suicide attempts are a significant risk factor for future suicidality. Therefore, the present military-based study examined the past suicidal behavior of soldiers who recently made a severe suicide attempt. Our sample consisted of 65 active-duty soldiers (61.5% males), between the ages of 18 and 28 years old (M = 20.4, SD ± 1.3). The inclusion criterion was a recent severe suicide attempt, requiring at least a 24 h hospitalization. This samp…
Social connectedness as a determinant of mental health
Public health and epidemiologic research have established that social connectedness promotes overall health. Yet there have been no recent reviews of findings from research examining social connectedness as a determinant of mental health. The goal of this review was to evaluate recent longitudinal research probing the effects of social connectedness on depression and anxiety symptoms and diagnoses in the general population. A scoping review was p…
Suicidal behaviour is pathological
Some have challenged the validity of labelling suicidal thoughts and behaviours (STB) as pathological. In this paper, we argue that STB is indeed pathological, thereby, situating suicide prevention within the realm of medicine, complicating calls for the legalisation of medical assistance in dying for individuals whose sole condition is psychiatric (psychiatric medical assistance in dying (MAID)). Evidence shows STB predicts the risk of suicide; …
Medicine (15 obras) · Psychology (14 obras) · Psychiatry (12 obras) · Suicide and Self-Harm Studies (9 obras) · Clinical Psychology (8 obras) · Poison control (8 obras) · Suicide prevention (7 obras) · Injury prevention (6 obras) · Medical emergency (6 obras) · Biology (5 obras)