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A new approach to prevent HIV transmission

Project Protect intervention for recently infected individuals

Bibliographic Data

ID19442072
AuthorsTetyana I Vasylyeva (0000-0002-9736-7022, Alliance for Public Health, corresponding author), R Friedman (0000-0003-2083-1226, National Development and Research Institutes), S R Friedman, Pavlo Smyrnov (0000-0003-4174-9432, National University of Kyiv-Mohyla Academy), K Bondarenko, K R Bondarenko (0000-0003-4147-1151, Alliance for Public Health)
Year2015
Volume27
Issue2
Pages223-228
Publication date2015-02-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2014.947913
PMID25244688
PMCIDPMC4524562
OpenAlexW2044132148
LanguageEN
Citations received5
References cited11

Past research suggests that as many as 50% of onward human immunodeficiency virus (HIV) transmissions occur during acute and recent HIV infection. It is clearly important to develop interventions which focus on this highly infectious stage of HIV infection to prevent further transmission in the risk networks of acutely and recently infected individuals. Project Protect tries to find recently and acutely infected individuals and prevents HIV transmission in their risk networks. Participants are recruited by community health outreach workers at community-based HIV testing sites and drug users' community venues, by coupon referrals and through referrals from AIDS clinics. When a network with acute/recent infection is identified, network members are interviewed about their risky behaviors, network information is collected, and blood is drawn for HIV testing. Participants are also educated and given prevention materials (condoms, syringes, educational materials); HIV-infected participants are referred to AIDS clinics and are assisted with access to care. Community alerts about elevated risk of HIV transmission are distributed within the risk networks of recently infected. Overall, 342 people were recruited to the project and screened for acute/recent HIV infection. Only six index cases of recent infection (2.3% of all people screened) were found through primary screening at voluntary counseling and testing (VCT) sites, but six cases of recent infection were found through contact tracing of these recently infected participants (7% of network members who came to the interview). Combining screening at VCT sites and contact tracing the number of recently infected people we located as compared to VCT screening alone. No adverse events were encountered. These first results provide evidence for the theory behind the intervention, i.e., in the risk networks of recently infected people there are other people with recent HIV infection and they can be successfully located without increasing stigma for project participants

Contact tracing · Disease · Family medicine · Outreach · Psychiatry · Psychological intervention · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Sex work and related issues · Internal Medicine

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    Open Access•Daniel J Escudero, Mark N Lurie et al.•BMC Public Health•2017

  • Analysis of HIV-1 recent infections and hotspot areas in a bordering area in Yunnan Province, China

    Open Access•Xiao Zhang, Lijuan Dong et al.•BMC Public Health•2025

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    Open Access•Ernest L Yufenyuy, Mervi Detorio et al.•PLOS Global Public Health•2022

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    Open Access•R Friedman, Martin J Downing et al.•AIDS and Behavior•2013

Unique citing works5
Citations per year0,56
Citation span2017 - 2025 (9)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 5
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