Sustainability of an evidence-based intervention supporting transition to independent care for youth living with HIV in Kenya

Bibliographic Data

ID19592498
AuthorsAlina Metje (0009-0008-0910-6713, University of Washington, corresponding author), Sarah Shaw (0000-0002-3517-0881, University of Washington, corresponding author), Cyrus Mugo (0000-0001-7516-2168, Kenyatta National Hospital, corresponding author), Mercy Awuor (Kenyatta National Hospital, corresponding author), Annabell Dollah (Kenyatta National Hospital, corresponding author), Hellen Moraa (0000-0001-8862-3058, Kenyatta National Hospital, corresponding author), Christine Kundu (0009-0005-3446-0915, Kenyatta National Hospital, corresponding author), Dalton Wamalwa (0000-0002-5510-462X, University of Nairobi, corresponding author), Grace John-Stewart, Grace John‐Stewart (0000-0002-4301-1573, University of Washington, corresponding author), Kristin Beima‐Sofie (0000-0002-3408-7410, University of Washington, corresponding author), Kristin Beima-Sofie, Irene Njuguna (0000-0003-4250-3231, University of Washington, corresponding author)
EditorsHenry Zakumumpa (0000-0002-8169-1151)
Year2025
Volume5
Issue1
Pagese0004111
Publication date2025-01-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0004111
PMID39804947
OpenAlexW4406311074
LanguageEN
References cited40

Integrating and sustaining evidence-based interventions (EBIs) in routine care is crucial to improving HIV treatment outcomes among youth living with HIV (YLH). However, EBIs are often not sustained post clinical trial. An Adolescent Transition Package (ATP) delivered by health care workers (HCWs) and tested in Kenya in 2021 significantly improved YLH readiness to transition to independent care. Post-trial, participating clinics could continue using the ATP. We conducted 30 in-depth interviews with health care workers to evaluate determinants of continued ATP implementation one-year post-trial. Interviews used semi-structured guides, informed by the Consolidated Framework for Implementation Research version 2.0 (CFIR v2.0). Transcripts were analyzed thematically to identify key influences of ATP sustainment and fidelity post-trial. Effective training during and after the trial, and continued internal and external support for implementation, were crucial for sustained acceptability and feasibility. In contrast, staff shortages and high turnover, lack of integration into the existing electronic medical system, and maintaining staff motivation were barriers to ATP sustainment. Implementation fidelity was limited by workforce constraints and HCW beliefs about the importance of individualizing content and delivery to be responsive to individual client needs. ATP adaptability afforded optimization of delivery to overcome workforce constraints and meet client needs, increasing HCW perceptions of feasibility and motivating continued use. Alignment between observed impact and care provision goals further motivated ongoing ATP utilization. Strategies to ensure continued training and integration of tools into existing systems have the potential to further enhance ATP sustainability

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